Обзоры литературы

doi: 10.25005/2074-0581-2020-22-4-580-594
НЕКОТОРЫЕ АСПЕКТЫ ЭПИДЕМИОЛОГИИ И ЭТИОПАТОГЕНЕЗА МЕТАБОЛИЧЕСКОГО СИНДРОМА

С.М. Абдуллозода

Кафедра эпидемиологии, Таджикский государственный медицинский университет им. Абуали ибни Сино, Душанбе, Республика Таджикистан

Проведён обзор литературных данных по важнейшим аспектам эпидемиологии, факторам риска и патогенезу метаболического синдрома (МС). Выявлено, что МС встречается приблизительно у четверти населения земли, и, несмотря на проведение широкомасштабных лечебно-профилактических и оздоровительных мероприятий в мировом масштабе, число лиц с МС имеет тенденцию к ежегодному увеличению, в особенности среди молодого трудоспособного возраста. В его генезе имеет значение множество факторов риска, в том числе генетическая предрасположенность, низкая физическая активность, нерациональное питание, курение, кишечная микробиота, синдром обструктивного апноэ сна и другие, роль большинства их которых необходимо изучить более углублённо. Для диагностики МС предложено множество критериев, каждый из которых имеет свои преимущества и недостатки. При МС страдает большинство органов и систем, и при сочетанном вовлечении сердечно-сосудистой, эндокринной, мочевыделительной, пищеварительной и респираторной систем отягощается течение МС. В связи с вышеперечисленным, имеется основание для проведения дальнейших научных исследований по выявлению причин и факторов риска развития МС, разработке путей профилактики, превентивной диагностики и раннего лечения МС.

Ключевые слова: метаболический синдром, эпидемиология, патогенез, сахарный диабет, инсулинорезистентность, ожирение, гиперхолестеринемия.

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Сведения об авторах:


Абдуллозода Саид Муртазо
кандидат медицинских наук, соискатель кафедры эпидемиологии, Таджикский государственный медицинский университет им. Абуали ибни Сино
ORCID ID: 0000-0003-0058-7633
SPIN-код: 5979-1928
Author ID: 991827
E-mail: saidxoja@gmail.com

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Абдуллозода Саид Муртазо
кандидат медицинских наук, соискатель кафедры эпидемиологии, Тад- жикский государственный медицинский университет им. Абуали ибни Сино

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