Literature Reviews

doi: 10.25005/2074-0581-2017-19-3-399-406
RADICAL SINGLE-STAGE OPERATIONS AT INTESTINAL OBSTRUCTION, CAUSED BY THE TUMOR OF THE LEFT HALF PART OF THE LARGE INTESTINE (CURRENT STATUS OF THE PROBLEMS)

D. A. Musoev1, M.K. Gulov1, E.L. Kalmykov2, A.R. Dostiev1, D.K. Mukhabbatov1, D.M. Kurbanov3

1Department of General Surgery № 1, Avicenna Tajik State Medical University, Dushanbe, Tajikistan
2Department of Science, Avicenna Tajik State Medical University, Dushanbe, Tajikistan
3Department of Operative Surgery and Topographic Anatomy, Avicenna Tajik State Medical University, Dushanbe, Tajikistan

In more than 40% of cases, colon cancer (CС) is diagnosed in stages III-IV, at the same time the resectability reaches 70-80%. The main priority of surgical intervention by obturation of intestinal obstruction at the first stage is the bowel emptying from the contents and the elimination of its obstruction. Intraoperative entero- and colon lavage with subsequent colosorption facilitate single-stage surgical interventions. When treating patients with decompensated intestinal obstruction, preference is given to more sparing and multi-stage surgical interventions. The key point of the operation is the removal of the tumor in full volume R0. Segmental left-sided colectomy can be performed in the presence of adequate edges of R0, as well as the conduct of lymphadenectomy. In the case of the presence of a locally advanced process involving neighboring organs, it is possible to perform a so-called «curative resection», an «an block» resection with complete or partial removal of the involved organs together with the tumor. In patients with compensated and subcompensated intestinal obstruction, it is possible to perform intestinal resection with the formation of a primary anastomosis. In recent years, endosurgical techniques for restoring the passage of intestinal contents, which can be considered as a method of preparing the patient for radical treatment, have become very popular in the treatment of patients with tumour obstruction. The possibility of open treatment of patients suffering from CC largely depends on the presence or absence of metastases in the liver. If their presence, in some cases, it is possible to perform anatomical resections of the affected areas of the liver. Early postoperative results of surgical treatment of patients after removal of large intestine tumours largely depend on the full preparation of the intestine, the presence of concomitant diseases, as well as the ways of protection of the anastomosis and its type.

Keywords: Intestinal obstruction, intestinal anastomosis, colon cancer, one-stage operations on the large intestine.

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References
  1. Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136(5):E359-86. Available from: http:// dx.doi.org/10.1002/ijc.29210. Epub 2014 Oct 9.
  2. Tsimmerman YaS. Kolorektal’nyy rak: sovremennoe sostoyanie problemy [Colorectal cancer: state-of-the-art]. Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii. 2012;22(4):5-16.
  3. Aleksandrov VB, Rahimova OYu. Kolorektal’nyy rak. Nekotorye voprosy diagnostiki i lecheniya [Colorectal cancer. Some questions of diagnosis and treatment]. Vrach. 2009;11:33.
  4. Artyukhov SV, Kubachyov KG, Muhiddinov ND. Endoskopicheskie vmeshatel’stva pri opuholevoy obturatsionnoy neprokhodimosti levykh otdelov obodochnoy kishki [Endoscopic interventions in obturation intestinal obstruction of left-sided colon]. Vestnik Avitsenny [Avicenna Bulletin]. 2015;1:25-8.
  5. Denisenko VL, Gain JuM. Palliativnoe lechenie patsientov s kolorektal’nym rakom, oslozhnyonnym kishechnoy neprokhodimost’yu [Palliative treatment if patients with colorectal cancer complicated by intestinal obstruction]. Ukrains’kiy zhurnal khіrurgіі. 2014;1:94-8.
  6. Ermolov AS, Rudin EP, Jun DD. Vybor metoda kKhirurgicheskogo lecheniya obturatsionnoy neprokhodimosti pri opukholyakh obodochnoy kishki [The choice of the method of surgical treatment of obstruction due a colonic tumors]. Khirurgiya. 2004:2:4-7.
  7. Belokonev VI, Fedorin AI. Opredelenie pokazaniy k nalozheniyu anastomozov i vyvedeniyu kishechnykh stom u bol’nykh s peritonitom i ostroy kishechnoy neprokhodimost’yu [Indications for anastomosis and intestinal stoma formation in patients with peritonitis and acute intestinal obstruction]. Vestnik Avitsenny [Avicenna Bulletin]. 2012;3:30-3.
  8. Chiarugi M, Galatioto C, Panicussi S, Scassa F, Zocco G, Seccia M. Oncologic colon cancer resection in emergency: are we doing enough? Surgical Oncology. 2007;16(1):S73–S77. Available from: http://dx.doi.org/10.1016/j. suronc.2007.10.019.
  9. Shimura T, Joh T. Evidence-based clinical management of acute malignant colorectal obstruction. J Clin Gastroenterol. 2016;50(4):273-85. Available from: http://dx.doi.org/10.1097/MCG.0000000000000475. Review.
  10. Tsarkov PV, Nikoda VV, Stamov VI, Markaryan DR, Tulina IA. Mul’tidistsiplinarnyy podkhod v planovoy khirurgii kolorektal’nogo raka u bol’nykh starcheskogo vozrasta [The efficacy of the multidisciplinary approach in colorectal cancer surgery in elderly patients]. Khirurgiya. 2012;2:4-13.
  11. Pomazkin VI. Dvukhetapnaya taktika lecheniya ostroy obturatsionnoy tolstokishechnoy neprokhodimosti opukholevogo geneza [Two-stage tactic of treatment of acute bowel obstruction due to colorectal carcinoma]. Vestnik Ural’skoy meditsinskoy akademicheskoy nauki. 2009;3:116-9.
  12. Kurbonov KM, Sharipov HYu, Khomidov MG. Sovremennye tekhnologii v kompleksnoy diagnostike nesostoyatel’nosti tolstokishechnykh anastomozov [Modern technologies in complex diagnosis of colonic anastomosis insufficiency]. Koloproktologiya. 2009;4:43-5.
  13. Tsarkov PV, Kravchenko AYu, Tulina IA, Bashankaev BN, Samofalova OYu. Paraaortal’naya limfadenektomiya so skeletizatsiey nizhney bryzheechnoy arterii v lechenii raka sigmovidnoy kishki [The paraaortic lymphadenectomy with the lower mesenteric artery sceletonization for the sigmoid cancer treatment]. Khirurgiya. 2012;7:41-8.
  14. Topuzov EG, Erokhina EA, Shishkina GA, Topuzov EE, Aliev KN. Profilaktika rasprostranyonnogo peritonita posle operatsiy po povodu raka tolstoy kishki [Diffuse peritonitis prophylaxis after colon cancer surgery]. Koloproktologiya. 2009;1:27-31.
  15. Radzikhovskiy AP, Mironenko AI, Rybyanets YuV. Tselesoobraznost’ enteral’noy korrektsii u patsientov s obturatsionnoy neprokhodimost’yu kishechnogo trakta [Expedience of enteral nutritional support for patients with acute cancer obstruction of intestine]. Ukrains’kiy zhurnal khіrurgii. 2009; 5: 145-147.
  16. Slesarenko AS, Turbanova EA. Rol’ enteral’nogo pitaniya v predoperatsionnoy podgotovke i vedenii rannego posleoperatsionnogo perioda u bol’nykh kolorektal’nym rakom [The role of enteral nutrition in preoperative preparation and management of the early postoperative period in patients with colorectal cancer]. Koloproktologiya. 2009;2:15-8.
  17. Cahill RA, Leroy J, Marescaux J. Localized resection for colon cancer. Surgical Oncology. 2009; 18(4): 334-42. Available from: http://dx.doi.org/ 10.1016/j. suronc.2008.08.004.
  18. Sasaki K, Kazama S, Sunami E, Tsuno NH, Nozawa H, Nagawa H, et al. Onestage segmental colectomy and primary anastomosis after intraoperative colonic irrigation and total colonoscopy for patients with obstruction due to left-sided colorectal cancer. Dis Colon Rectum. 2012;55(1):72-8. Available from: http://dx.doi.org/10.1097/DCR.0b013e318239be5e.
  19. Labianca R, Beretta GD, Kildani B, Milesi L, Merlin F, Mosconi S, et al. Colon cancer. Crit Rev Oncol. 2010; 74(2):106-33. Available from: http://dx.doi. org/10.1016/j.critrevonc.2010.01.010.
  20. Suzuki T, Sadahiro S, Maeda Y, Tanaka A, Okada K, Kamijo A. Optimal duration of prophylactic antibiotic administration for elective colon cancer surgery: A randomized, clinical trial. Surgery. 2011;149(2):171-8. Available from: http:// dx.doi.org/10.1016/j.surg.2010.06.007.
  21. Schneider EB, Hyder O, Brooke BS, Efron J, Cameron JL, Edil BH, et al. Patient readmission and mortality after colorectal surgery for colon cancer: impact of length of stay relative to other clinical factors. J Am Coll Surg. 2012;214(4):390-8; discussion 398-9. Available from: http://dx.doi. org/10.1016/j.jamcollsurg.2011.12.025.
  22. Dekker JW, Liefers GJ, de Mol van Otterloo JC, Putter H, Tollenaar RA. Predicting the risk of anastomotic leakage in left-sided colorectal surgery using a colon leakage score. J Surg Res. 2011; 166(1):e27-34. Available from: http://dx.doi.org/10.1016/j.jss.2010.11.004.
  23. Denisenko VL, Gain YuM. Oslozhneniya kolorektal’nogo raka: problemy i perspektivy [Complications of colorectal cancer: problems and prospects]. Novosti khirurgii. 2011;19(1):103-11.
  24. Totikov VZ, Totikov MZ, Zuraev KE, Totikov ZV. Kombinirovannoe lechenie raka obodochnoy kishki, oslozhnyonnogo narusheniem kishechnoy prokhodimosti [Combined treatment of colon cancer, complicated by violation of intestinal patency]. Koloproktologiya. 2008; 1:58.
  25. Kanikovsky OE, Androsov SI, Pavlik IV, Rautskis VA, Nadolsky VO. Lechenie obturatsionnoy neprokhodimosti tolstogo kishechnika opukholevogo geneza [The treatment of patients with colorectal cancer complicated acute intestinal obstruction]. Ukrains’kiy zhurnal khіrurgii. 2009;5:103-5.
  26. Bailey HR, Billingham RP, Stamos MJ, Snyder MJ. Colorectal Surgery. Philadelphia, PA: Elsevier Health Sciences; 2013. 540 p.
  27. Shahidov AV, Laganin AA, Ershov VV, Kleymentyev EV. Sochetannoe endoskopicheskoe lechenie raka sigmovidnoy kishki, oslozhnyonnogo kishechnoy neprokhodimost’yu, u patsienta s krayney stepen’yu ozhireniya [Combined endoscopic therapy of sigmoid colon cancer complicated by bowel obstruction in an extremely obese patient]. Sovremennye tekhnologii v meditsine. 2014;6(1):118-20.
  28. Shapkin YuG, Uryadov SE, Chalyk YuV, Potahin SN. Endoskopicheskaya rekanalizatsiya tolstoy kishki pri opukholevoy neprokhodimosti [Endoscopic recanalization of colon at tumor impassability]. Saratovskiy nauchnomeditsinskiy zhurnal. 2010;6(3):727-9.
  29. Antadze AA, Lekvtadze NI, Chikobava GI, Gvantseladze GB. KKhirurgicheskoe lechenie oslozhnyonnykh form kolorektal’nogo raka [Surgical treatment for complicated forms of colorectal cancer]. Georgian Medical News. 2013;12(225):7-11.
  30. Lupaltsov VI, Yagnyuk AI, Dekhtyaruk IA, Panarin AI, Voroshchuk RS. Intraabdominal’naya gipertenziya u bol’nykh s ostroy tolstokishechnoy neprokhodimost’yu [Intraabdominal hypertension in patients with acute large intestinal obstruction]. Ukrains’kiy zhurnal khіrurgii. 2011;5:100-2.
  31. Aliev AR, Kulieva NG, Iskenderova ShR. Khirurgicheskoe lechenie bol’nykh s oslozhnyonnym klinicheskim techeniem kolorektal’nogo raka [Surgical treatment of patients with complicated clinical course of colorectal cancer]. Koloproktologiya. 2009;3:36-8.
  32. Belyanskiy LS. Khirurgicheskoe lechenie bol’nykh obstruktivnym rakom levoy poloviny tolstoy kishki [Surgical treatment of patients with obstructive cancers of the left half of the large intestine]. Kharkіvs’ka khіrurgіchna shkola. 2010;6:11-4.
  33. Kurbonov KM, Sharipov HYu, Abdulloev FM. Sovremennye metody diagnostiki i lecheniya raka tolstoy kishki, oslozhnyonnogo kishechnoy neprokhodimost’yu [Up to date diagnostic tools of bowel obstruction caused by colonic cancer]. Koloproktologiya. 2013;3:15-20.
  34. Makarov OG. Vybor ratsional’noy taktiki lecheniya raka tolstoy kishki, oslozhnyonnogo kishechnoy neprokhodimost’yu, v usloviyakh oblastnogo koloproktologicheskogo statsionara [Choice of rational treatment of colorectal cancer complicated by ileus at the setting of regional coloproctological hospital]. Rossiyskiy zhurnal gastroenterologii, gepatologii i koloproktologii. 2007;2:75-9.
  35. Popov DE, Semyonov AV, Grigoryan VV, Lisichkin AV, Vasilyev SV. Khirurgicheskoe lechenie kishechnoy neprokhodimosti u bol’nykh obturiruyushchim rakom levykh otdelov tolstoy kishki [Surgical treatment of intestinal impassability in obstruction left branch colon cancer]. Vestnik Sankt-Peterburgskogo universiteta. 2009;11(2):100-7.
  36. Boyko VV, Tishchenko AM, Skoryy DI, Smachilo RM, Kozlova TV. Retrospektivnyy analiz lecheniya pervichnogo i metastaticheskogo raka tolstoy kishki: pyatiletniy opyt [Retrospective analysis of treatment of primary and metastatic colon cancer: Five-year experience]. Ukrainskiy zhurnal khirurgii. 2012;4(19):16-24.
  37. Bondar GV, Basheev VH, Yakovets YI, Borota AV, Psaras GG, Zolotukhin SE, i dr. Pervichno-vosstanovitel’naya taktika khirurgicheskogo lecheniya raka tolstoy kishki, oslozhnyonnogo polnoy kishechnoy neprokhodimost’yu [Initiallyrestorative surgical treatment tactics of colon cancer complicated with ileus]. Ukrains’kiy zhurnal khіrurgii. 2009;1:16-8.
  38. Boyko VV, Savvy SA, Starikova AB, Novikov YA, Goloborodko NN. Taktika khirurgicheskogo lecheniya bol’nykh mestnorasprostranyonnym i metastaticheskim rakom obodochnoy kishki [Surgical treatment of patients with locally advanced and metastatic colon cancer]. Ukrains’kiy zhurnal khіrurgii. 2011;6:126-8.
  39. Vorobyev GI, Shelygin YuA, Frolov SA, Shakhmatov DG. Sravnitel’nyy analiz laparoskopicheskikh rezektsiy obodochnoy kishki s ruchnoy assistentsiey i laparoskopicheski-assistiruemykh vmeshatel’stv [Comparative analysis of laparoscopic resections of the colon with manual assistance and laparoscopically assisted interventions]. Koloproktologiya. 2008;4:17-22.
  40. Antoniou SA, Antoniou GA, Koch OO, Pointner R, Granderath FA. Robotassisted laparoscopic surgery of the colon and rectum. Surg Endosc. 2012;26(1):1-11. Available from: http://dx.doi.org/10.1007/s00464-011- 1867-y. Epub 2011 Aug 20. Review.
  41. Kirat HT, Kiran RP, Lian L, Remzi FH, Fazio VW. Influence of stapler size used at ileal pouch-anal anastomosis on anastomotic leak, stricture, long-term functional outcomes, and quality of life. Am J Surg. 2010;200(1):68-72. Available from: http://dx.doi.org/10.1016/j.amjsurg.2009.06.036.
  42. Colon Cancer Laparoscopic or Open Resection Study Group: Buunen M, Veldkamp R, Hop WC, Kuhry E, Jeekel J, Haglind E, et al. Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomized clinical trial. Lancet Oncol. 2009;10(1):44-52. Available from: http://dx.doi.org/10.1016/S1470-2045(08)70310-3.
  43. Kostyuk IP, Shestaev AYu, Krestyaninov SS, Vasilyev LA, Karandashov VK, Zaitsev AE. Podvzdoshno-kishechnyy J-rezervuar v ortotopicheskoy rekonstruktsii mochevogo puzyrya [Intestinal J-pouch in the orthotopic bladder reconstruction]. Vestnik Rossiyskoy voenno-meditsinskoy akademii. 2012;3:46-51.
  44. Gostkin PA, Sazhin VP, Syatkin DA. Metodika formirovaniya mezhkishechnykh anastomozov pri laparoskopicheskikh operatsiyakh na tolstoy kishke [The procedure for the formation of interintestinal anastomoses in laparoscopic operations on the large intestine]. Koloproktologiya. 2008;1:56.
  45. Sazhin VP, Gostkin PA, Syatkin DA. Neposredstvennye rezul’taty laparoskopicheskikh operatsiy pri kolorektal’nom rake [Immediate results of laparoscopic operations in colorectal cancer]. Koloproktologiya. 2008;1:57.
  46. Konovalov DYu. Mikrokhirurgicheskie tekhnologii v khirurgii obodochnoy kishki [Microsurgical technologies in colon surgery]. Koloproktologiya. 2008;4:28-31.
  47. Tatyanchenko VK, Koryakina AA, Chubaryan KA, Frolkin VI. Sposoby zashhity anastomoza pri operatsiakh na obodochnoy kishke [Methods of protecting anastomosis during operations on the colon]. Koloproktologiya. 2008; 1:53.
  48. Maskin SS, Khomochkin VV, Starovidchenko SA. Odnoryadnyy nepreryvnyy i dvuryadnyy shov pri kolorektal’nykh anastomozakh [Single-row continuous and double-row seam in colorectal anastomoses]. Koloproktologiya. 2008;1:54.
  49. Makhankov DO, Vazhenin AV, Sidelnikov SYu. Taktika lecheniya bol’nykh zlokachestvennymi novoobrazovaniyami levoy poloviny tolstoy kishki, oslozhnyonnymi obturatsionnoy kishechnoy neprokhodimost’yu [Treatment of patients with left-side colon cancer complicated by occlusive ileus]. Sibirskiy onkologicheskiy zhurnal. 2007;1:63-6.
  50. Shevchenko VP, Konanichin VI, Solodchenko MI, Bratushka VA, Sobolev JI, Shevchenko VV. Operatsiya Gartmana v urgentnoy khirurgii oslozhnyonnogo kolorektal’nogo raka [Hartmann’s operation in urgent surgery of complicated colorectal cancer]. Ukrains’kiy zhurnal khіrurgii. 2011;4:119- 21.
  51. Shaprinskiy VO, Kaminskiy OA, Biloshchitsiy VF, Voznyuk SV. Rekonstruktivnovosstanovitel’nye operatsii v koloproktologii [Reconstructive restorative operations in coloproctology]. Ukrains’kiy zhurnal khіrurgii. 2011; 5:170-2
  52. Timofeev YuM, Barsukov YuA, Barykina OA. Rekonstruktivno vosstanovitel’nye operatsii po metodu Dyuamelya posle operatsii Gartmana [Reconstructive operations using Duhamel technique after Hartmann’s operation]. Koloproktologiya. 2007;3:27-8.
  53. Gyulmamedov FI, Polunin GE, Makienko EG. Vybor metoda vosstanovleniya kishechnoy nepreryvnosti posle operatsii Gartmana [Choice of method of renewal intestinal to continuity after Hartmann’s operation]. Ukrains’kiy zhurnal khіrurgii. 2009;2:53-5.
  54. Groshilin VS, Sultanmuradov MI, Moskovchenko AN, Petrenko NA. Sovremennye aspekty profilaktiki oslozhneniy posle obstruktivnykh rezektsiy distal’nykh otdelov tolstoy kishki [Modern aspects of prevention of complications after obstructive resection of the distal colon]. Fundamental’nye issledovaniya. 2013.9(1):24-7.
  55. Timerbulatov VM, Fayazov RR, Mekhdiev DI, Akhmerov RR, Timerbulatov ShV, Gareev RN, i dr. Optimizatsiya podgotovki bol’nykh k rasshirennym operativnym vmeshatel’stvam pri oslozhnyonnoy forme raka tolstoy kishki [Optimization of preoperative care in patients with complicated colon carcinomas]. Koloproktologiya. 2013;2:19-22.
  56. Ioffe IV, Khunov YuA, Shor NA, Andreeva IV, Levina VP, Zelyonyy II, i dr. Osobennosti klinicheskogo techeniya i khirurgicheskoy taktiki pri ostroy tolstokishechnoy neprokhodimosti [The peculiarities of clinical manifestations and surgical tactics in acute colon ileus]. Ukrains’kiy zhurnal khіrurgii. 2009;5:97-100
  57. Midlenko VI, Barinov DV, Zaytsev AV, Smolkina AV, Zaytseva OB, Doyko MI, i dr. Perioperatsionnye oslozhneniya v khirurgii raka tolstogo kishechnika [Perioperative complications in surgery of the colon cancer]. Fundamental’nye issledovaniya. 2013;5:96-100.
  58. Bass G, Fleming C, Conneely J, Martin Z, Mealy K. Emergency first presentation of colorectal cancer predicts significantly poorer outcomes: a review of 356 consecutive Irish patients. Dis Colon Rectum. 2009;52(4):678-84. Available from: http://dx.doi.org/10.1007/DCR.0b013e3181a1d8c9.
  59. Rasulov SR, Karimov AM. Analiz zabolevaemosti kolorektal’nym rakom v Respublike Tadzhikistan [Analysis of morbidity of colorectal cancer in Republic of Tajikistan]. Vestnik poslediplomnogo obrazovaniya v sfere zdravookhraneniya. 2015;1:57-60.
  60. Artyukhov SK, Mukhiddinov ND, Kubachyov KG, Zarkua NE. Radikal’nye operatsii pri rake rektosigmoidnogo otdela i pryamoy kishki, oslozhnyonnom kishechnoy neprokhodimost’yu [Radical operation in cancer of rectosigmoid and rectum, complicated by intestinal obstruction]. Vestnik poslediplomnogo obrazovaniya v sfere zdravookhraneniya. 2016;3:15-9.
  61. Kao LS, Millas SG. Predicting the risk of anastomotic leakage in left-sided colorectal surgery using a colon leakage score. J Surg Res. 2012;173(2):246-8. Available from: http://dx.doi.org/10.1016/j.jss.2011.01.044.
  62. Fraccalvieri D, Biondo S, Saez J, Milan M, Kreisler E, Golda T, et al. Management of colorectal anastomotic leakage: differences between salvage and anastomotic takedown. Am J Surg. 2012;204(5):671-6. Available from: http://dx.doi.org/10.1016/j.amjsurg.2010.04.022.

Authors' information:


Musoev Dilovarsho Askarovich,
Postgraduate Student of the Department of General Surgery № 1, Avicenna Tajik State Medical University

Gulov Mahmadsho Kurbonalievich,
Doctor of Medical Sciences, Full Professor, Professor of the Department of General Surgery № 1, Avicenna Tajik State Medical University

Kalmykov Egan Leonidovich,
Candidate of Medical Sciences, Research Fellow of the Department of Science, Avicenna Tajik State Medical University

Dostiev Ashur Rajabovich,
Doctor of Medical Sciences, Full Professor, Professor of the Department of General Surgery № 1, Avicenna Tajik State Medical University

Mukhabbatov Dzhiyonkhon Kurbonovich,
Doctor of Medical Sciences, Assistant of the Department of General Surgery № 1, Avicenna Tajik State Medical University

Kurbanov Jurabek Muminovich,
Candidate of Medical Sciences, Associate Professor, Head of the Department of Operative Surgery and Topographic Anatomy, Avicenna Tajik State Medical University

Conflicts of interest: No conflict

Address for correspondence:


Musoev Dilovarsho Askarovich

Postgraduate Student of the Department of General Surgery № 1, Avicenna Tajik State Medical University

Tel. : (+992) 918 852358

E-mail: egan0428@mail.ru