Obstetrics and Gynecology

doi: 10.25005/2074-0581-2019-21-1-26-32
ASSESSMENT OF RISK FACTORS OF PREMATURE BIRTH

A.E. Shklyaev1, M.V. Semyonova2, A.S. Lyalina3, I.E. Maksimov3

1Department of Faculty Therapy with Courses of Endocrinology and Hematology, Izhevsk State Medical Academy, Izhevsk, Russian Federation
2Department of Obstetrics and Gynecology, Izhevsk State Medical Academy, Izhevsk, Russian Federation
3Medical Faculty, Izhevsk State Medical Academy, Izhevsk, Russian Federation

Objective: Assessment of the significance of possible etiological factors in the development of early-premature birth in the Udmurt Republic.

Methods: The main monitoring group consisted of 94 women with extremely early premature birth, the comparison group – 94 women with spontaneous childbirth in time. The estimation of the significance of risk factors was carried out by means of determination of relative risk value (RR), which characterizes the relationship between exposure and pathology. The data obtained as a result of the research are processed by generally accepted methods of variation statistics.

Results: The obtained data on the significant influence of the morphofunctional state of the placenta (chronic placental insufficiency, relative risk, RR=3.4), premature rupture of the fetal membranes (RR=3.9), cervical insufficiency (RR=23) for the development of early premature childbirth. The somatic history of women with extremely early premature birth is a pathology of the cardiovascular system (arterial hypertension, RR=5.7), liver and biliary tract (dyskinesia, RR=3.7), iron deficiency anemia (RR=5.0), what is important for the adequate development and functioning of the placenta.

Conclusions: Premature birth still remains an important problem in obstetrics, neonatology, and pediatrics. Of the risk factors we have identified for the Udmurt Republic, the most important consider the cervical insufficiency, premature birth in the anamnesis, inflammatory processes of the cervix, etc. Pregravid preparation taking into account these risk factors, and also the correction of extragenital pathology, can help to reduce the incidence of early premature birth.

Keywords: Premature birth, early premature birth, risk factors.

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Authors informations:

Shklyaev Aleksey Evgenievich , Doctor of Medical Sciences, Professor of the Department of Faculty Therapy with Courses of Endocrinology and Hematology, Vice Rector for Science, Izhevsk State Medical Academy

Semyonova Margarita Vitalievna , Candidate of Medical Sciences, Associate Professor, Head of the Department of Obstetrics and Gynecology, Izhevsk State Medical Academy

Lyalina Anastasia Sergeevna , 6th year Student of the Medical Faculty, Izhevsk State Medical Academy

Maksimov Ivan Evgenievich , 6th year Student of the Medical Faculty, Izhevsk State Medical Academy

Address for correspondence:

Maksimov Ivan Evgenievich
6th year Student of the Medical Faculty, Izhevsk State Medical Academy

426034, Russian Federation, Izhevsk, str. Communarov, 281-109

Tel.: +7 (982) 7967201

E-mail: ivan.maksimov.1995@mail.ru

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