Literature Reviews

doi: 10.25005/2074-0581-2019-21-1-136-140 10.25005/2074-0581-2019-21-1-136-140
COMPLEX DIAGNOSTICS AND METHODS OF TREATMENT OF THE SYNDROME OF ENTERAL INSUFFICIENCY IN PATIENTS WITH ACUTE PANCREATITIS

S.G. Ali-Zade, Sh.K. Nazarov, P.K. Kholmatov, R.A. Dodikhudoev

Department of Surgical Diseases № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan

In the given literary review are discussed the actual problems of diagnosis and treatment of the syndrome of enteral insufficiency, occurs against the background of acute pancreatitis. In patients suffering from acute pancreatitis, up to 80% of cases, enteral insufficiency syndrome (EIS) occurs, aggravating the processes of endotoxicosis. To date, the timely detection of EIS through the use of modern methods of research of detecting disorders is still considered to be influencing disorders of intestinal function. For full diagnosis of EIS are modern laboratory and instrumental studies, such as radiographic, ultrasound, electrogastroenterography, and also the bacteriological research of feces. Prokinetics (ganaton, metoclopramide derivatives, etc.), early intestinal lavage, and cleansing enemas are more often used to stimulate the intestine. It is considered that such a combined application of treatment methods has a great effect against enteroparesis which contributes to the consolation of the results of the EIS in acute pancreatitis. It should be noted that recently a great interest in scientists cause the issues of early enteral probe feeding. It was determined that the best results were the treatment of patients with the use of enteral probe feeding in combination with selective decontamination of the gastrointestinal tract. Thus, therapeutic measures for EIS are aimed at resolving enteroparesis. However, these therapeutic measures need further research as well as aspects of preventing the development of functional bowel disorders.

Keywords: Enteral insufficiency syndrome, acute pancreatitis, diagnosis, treatment.

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Authors' information:


Ali-Zade Sukhrob Gaffarovich
Candidate of Medical Sciences, Assistant of the Department of Surgical Diseases № 1, Avicenna Tajik State Medical University

Nazarov Shokhin Kuvvatovich
Doctor of Medical Sciences, Full Professor, Head of the Department of Surgical Diseases № 1, Avicenna Tajik State Medical University

Kholmatov Pulat Kadyrovich
Candidate of Medical Sciences, Associate Professor, Associate Professor of the Department of Surgical Diseases № 1, Avicenna Tajik State Medical University

Dodikhudoev Rakhmatullo Alamshoevich
Postgraduate Student, Department of Surgical Diseases № 1, Avicenna Tajik State Medical University

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from manufacturers of medicines and medical equipment.

Conflicts of interest: No conflict

Address for correspondence:


Ali-Zade Sukhrob Gaffarovich
Candidate of Medical Sciences, Assistant of the Department of Surgical Diseases № 1, Avicenna Tajik State Medical University

734003, Republic of Tajikistan, Dushanbe, Rudaki Ave., 139

Tel.: +992 (928) 217755

E-mail: suhrob_a@mail.ru