Literature Reviews

doi: 10.25005/2074-0581-2020-22-1-112-119
CLINICAL AND SOCIAL ASPECTS OF HEROIN ADDICTION: MODERN STATE OF ISSUE

Sh.M. Gulyamov1, N.M. Sharapova1, Yu.D. Krivoruchko2

1Department of Psychiatry and Narcology named after Prof. M.G. Gulyamov, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
2V.P. Serbsky National Medical Research Center of Psychiatry and Narcology, Moscow, Russian Federation

The article provides a brief overview of the literature, which deals with the issues of heroin addiction, its history, prevalence, statistics, clinical characteristics, diagnostics, prevention and countermeasures, as well as programs aimed at social rehabilitation and harm reduction from injecting drug use. Issues such as physiological foundations and features of disease and remission formation, withdrawal, motivational attitudes of drug users, structure users of narcotic substances, the impact of pre-morbid features, socio-demographic, clinical-dynamic, regional and gender aspects of heroin addiction, and also existing approaches to therapeutic and preventive measures are considered in narcology. Medical and social consequences expressed in the form of the spread of hemo-contact infections, such as HIV/AIDS and viral hepatitis; risky behavior and its impact on the growth of sexually transmitted infections; reducing and completely losing social status; suicide-aggressive actions have been studied. The analysis of data on the study of the prognostic value of the socio-demographic and clinical-dynamic characteristics of heroin addiction and its effect is provided on the outcome of the disease.

Keywords: Drugs, drug addiction, heroin addiction, opioids, addiction treatment.

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References
  1. Safonov OA, Dmitrieva TB, Klimenko TV, Kozlov AA. Istoriya potrebleniya. rasprostranyonnost’ i kontrol’ za nezakonnym oborotom opiatov po regionam mira [Consumption history, prevalence and control of illicit trafficking in opiates by region of the world]. Narkologiya. 2011;4:36-43.
  2. Idrisov B, Lunze K, Cheng DM, Blokhina E, Gnatienko N, Quinn E, et al. Role of substance use in HIV care cascade outcomes among people who inject drugs in Russia. Addict Sci Clin Pract. 2017;12(1):30.
  3. Dauria EF, McWilliams MA, Tolou-Shams M. Substance use prevention and treatment interventions for court-involved, non-incarcerated youth. Brief Intervent Adolesc Alcohol Substance Abuse. 2018;16:213.
  4. Larochelle MR, Bernson D, Land T, Stopka TJ, Wang N, Xuan Z, et al. Medication for opioid use disorder after nonfatal opioid overdose and association with mortality. Ann Intern Med. 2018;169(3):137-45.
  5. Gulyamov MG. Psikhiatriya [Psychiatry]. Dushanbe, RT: Irfon; 1993. 460 p.
  6. Zobin ML, Yarovoy VS. Opioidnaya zavisimost’ i upravlenie avtotransportom [Opioid dependence and motor vehicle management]. Narkologiya. 2010;8:90-7.
  7. Pyatnitskaya IN. Narkomaniya [Addiction]. Moscow, RF: Meditsina; 1994. 526 p.
  8. Ivanets NN. Rukovodstvo po narkologii [Addiction Guide]. Moscow, RF: Meditsinskoe informatsionnoe agentstvo; 2008. 944 p.
  9. Mendelevich VD. (red.) Rukovodstvo po addiktologii [Addictology Guide]. Saint Petersburg, RF: Rech’; 2007. 768 p.
  10. Lozovoy VV. Profilaktika narkomanii:shkola,sem’ya [Drug prevention:school, family]. Ekaterinburg, RF: Izdatel’stvo Ural’skogo universiteta; 2009. 168 p.
  11. Jones CM, Campopiano M, Baldwin G, McCance-Katz E. National and state treatment need and capacity for opioid agonist medication-assisted treatment. Am J Public Health. 2015;105(8):55-63.
  12. Klimas J, Cullen W, Field CA. Problem alcohol use among problem drug users: development and content of clinical guidelines for general practice. Ir J Med Sci. 2014;183(1):89-101.
  13. Feldman N, Chatton A, Khan R, Khazaal Y, Zullino D. Alcohol-related brief intervention in patients treated for opiate or cocaine dependence: a randomized controlled study. Subst Abuse Treat Prev Policy. 2011;6:22.
  14. Compton WM, Jones CM, Baldwin GT. Relationship between non-medical prescription-opioid use and heroin use. New England Journal of Medicine. 2016;154:163.
  15. Shabanov PD. Narkologiya. Rukovodstvo [Narcology. Guide]. Moscow, RF: GEOTAR-Media; 2015. 832 p.
  16. Gannushkin PB. Klinika psikhopatiy, ikh statika, dinamika, sistematika [Clinic of psychopathies, theirstatics, dynamics,systematics]. Nizhniy Novgorod, RF: Izdatelstvo NGMA; 1998. 128 p.
  17. Rybakova KV, Ilyuk RD, Pushina VV, Vuks AYa, Anuchina AA, Krupitskiy EM. Izuchenie vzaimosvyazi sotsial’no-demograficheskikh, klinicheskikh kharakteristik i pokazateley anozognozii pri opioidnoy zavisimosti [The study of the relationship of socio-demographic, clinical characteristics and indicators of anosognosia with opioid dependence]. Voprosy narkologii. 2018;5:63-6.
  18. Hasin DS. US epidemiology of cannabis use and associated problems. Neuropsychopharmacology. 2017;43:195.
  19. Feder KA, Krawczyk N, Saloner B. Medication-assisted treatment for adolescents in specialty treatment for opioid use disorder. J Adolesc Health. 2017;60(6):747-50.
  20. Iskandarov RR, Masagutov RM, Mukhitova IE, Khramova DG. Rol’ alkogolizma i geroinovoy narkomanii v geneze agressivnogo povedeniya osuzhdyonnykh muzhchin s posttravmaticheskim stressovym rasstroystvom (PTSR) [The role of alcoholism and heroin addiction in the genesis of aggressive behavior of convicted men with post-traumatic stress disorder (PTSD)]. Narkologiya. 2011;11:57-62.
  21. Addiktivnye rasstroystva u studentov uchebnykh zavedeniy raznykh tipov Zabaykal’skogo kraya [Addictive disorders in students of educational institutions of different types of Trans-Baikal Territory]. Voprosy narkologii. 2018;9:7-16.
  22. Bogdanov SI, Chadova EA, Vins LV, Retyunskiy KYu, Ogudov AS, Bogdanova SS. Klyuchevye kharakteristiki aktivnykh potrebiteley narkoticheskikh sredstv v otnoshenii potrebleniya osnovnogo narkoticheskogo sredstva [Key characteristics of active drug users in relation to consumption of the main drug]. Narkologiya. 2012;5:46-52.
  23. Hadland SE, Marshall BD, Kerr T, Zhang R, Montaner JS, Wood E. A comparison of drug use and risk behavior profiles among younger and older street youth. Subst Use Misuse. 2011;46(12):1486-94.
  24. Lloyd JJ, Ricketts EP, Havens JR, Cornelius LJ, Bishai D, Huettner S, et al. The relationship between lifetime abuse and suicidal ideation in a sample of injection drug users. J Psychoactive Drugs. 2007;39(2):159-66.
  25. Klimenko TV, Kozlov AA, Didenko ES. Alternativnoe lechenie pravonarushiteley ot narkomanii kak effektivnaya forma profilaktiki retsidivnoy prestupnosti [Alternative drug abuse treatment for offenders as an effective form of prevention of recidivism]. Narkologiya. 2012;4:19-24.
  26. Malakhov MN. In’ektsionnoe potreblenie narkotikov i mery protivodeystviya so storony narkologicheskoy sluzhby [Injecting drug use and drug control measures]. Vestnik Avitsenny [Avicenna Bulletin]. 2008;2:89-92.
  27. Hakkinen M, Launiainen T, Vuori E, Ojanpera I. Comparison of fatal poisonings by prescription opioids. Forensic Sci Int. 2012;222(1-3):327-31.
  28. Sadvakasova GA, Bektemirova BK, Sultanova KE. Sovremennye tendentsii v izuchenii problem VICh-infitsirovannykh beremennykh zhenshchin, yavlyayushchikhsya potrebitelyami in’’ektsionnykh narkotikov [Current trends in studying the problems of HIV-infected pregnant women who are injecting drug users]. Voprosy narkologii Kazakhstana. 2009;9(1):31-2.
  29. Cherepkova EV. Osnovnye simptomokompleksy lichnostnykh rasstroystv u lits, upotreblyayushchikh narkoticheskie veshchestva [The main symptoms of personality disorders in people who use drugs]. Narkologiya. 2011;1:70-4.
  30. Savonova IV. Opiynaya narkomaniya, assotsiirovannaya virusnym gepatitom «B» i «C», kliniko-dinamicheskiy aspect [Opium addiction associated with viral hepatitis “B” and “C”, clinical and dynamic aspect]. Narkologiya. 2005;12:58-61.
  31. Koren SV, Dolzhanskaya NA. Zloupotreblenie psikhoaktivnymi veshchestvami kak faktor rasprostraneniya infektsiy, peredayushchikhsya polovym putyom [Substance abuse as a factor in the spread of sexually transmitted infections]. Voprosy narkologii. 2018;9:80-92.
  32. Rotondi NK, Strike C, Kolla G, Rotondi MA, Rudzinski K, Guimond T, et al. Transition to injection drug use: the role of initiators. AIDS Behav. 2014;18(3):486- 94.
  33. Westergaard RP, Genz A, Panico K, Surkan PJ, Keruly J, Hutton HE, et al. Acceptability of a mobile health intervention to enhance HIV care coordination for patients with substance use disorders. Addict Sci Clin Pract. 2017;12(1):11.
  34. Claborn K, Becker S, Ramsey S, Rich J, Friedmann P. Mobile technology intervention to improve care coordination between HIV and substance use treatment providers: development, training, and evaluation protocol. Addict Sci Clin Pract. 2017;12(1):8.
  35. Palatkin VYa, Vetrova MV, Bushara NM, Yaroslavtseva TS, Blokhina EA, Krupitskiy EM, i dr. Vyrazhennost’ psikhopatologicheskikh simptomov, kachestvo zhizni i rasprostranyonnost’ VICh-infektsii sredi bolnykh s sindromom zavisimosti ot opioidov [The severity of psychopathological symptoms, quality of life and the prevalence of HIV infection among patients with opioid dependence syndrome]. Voprosy narkologii. 2018;5:89-92.
  36. Koshkina EA, Kirzhanova VV. Sovremennoe sostoyanie narkosituatsii v Rossii po dannym gosudarstvennoy statistiki [The current state of the drug situation in Russia according to state statistics]. Psikhicheskoe zdorov’e. 2009;8:22-7.
  37. Olfson M, Crystal S, Wall M, Wang S, Liu S-M, Blanco C. Causes of death after nonfatal opioid overdose. JAMA Psychiatry. 2018;75(8):820-7.
  38. Hartzler B, Donovan DM, Huang Z. Comparison of opiate-primary treatment seekers with and without alcohol use disorder. J Subst Abuse Treat. 2010;39(2):114-23.
  39. Zokirov AH. Sotsio-demograficheskie osobennosti zavisimykh potrebiteley narkotikov [Socio-demographic characteristics of addicted drug users]. Avchi Zukhal. 2015;3:41.
  40. Sharopova NM, Dzhobirov AR. Profilaktika, zamestitel’naya terapiya i mediko-sotsial’naya reabilitatsiya pri opioidnoy zavisimosti [Prevention substitution therapy and medical and social rehabilitation for opioid dependence]. Dushanbe, RT: Matbuot; 2017. 28 p.

Authors' information:


Gulyamov Shodibek Minkhozhevich
Competitor of the Department of Psychiatry and Narcology named after Professor M.G. Gulyamov, Avicenna Tajik State Medical University
ORCID ID: 0000-0002-5352-8867
Researcher ID: D-4440-2019
E-mail: shodibek.gulyamov@gmail.com

Sharapova Nigina Minkhozhevna
Doctor of Medical Sciences, Full Professor, Head of the Department of Psychiatry and Narcology named after Professor M.G. Gulyamov, Avicenna Tajik State Medical University
ORCID ID: 0000-0002-9257-9683
Researcher ID: AAB-4824-2020
Author ID: 477931
E-mail: sharopova@yandex.ru

Krivoruchko Yuriy Davydovich
Doctor of Medical Sciences, Head of the Department of Continuing Professional Education, V.P. Serbsky National Medical Research Center of Psychiatry and Narcology
ORCID ID: 0000-0001-6062-928X
Author ID: 561516
E-mail: otdel.kvn@mail.ru

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:


Gulyamov Shodibek Minkhozhevich
Competitor of the Department of Psychiatry and Narcology named after Professor M. G. Gulyamov, Avicenna Tajik State Medical University

734003, Republic of Tajikistan, Dushanbe, Rudaki Ave., 139

Tel.: +992 (902) 202210

E-mail: shodibek.gulyamov@gmail com