Literature Reviews
doi: 10.25005/2074-0581-2020-22-4-580-594
SOME ASPECTS OF EPIDEMIOLOGY AND ETIOPATHOGENESIS OF METABOLIC SYNDROME

S. M. Abdullozoda

Department of Epidemiology, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan

A review of literature data carried out on the most important aspects of epidemiology, risk factors and pathogenesis of metabolic syndrome (MS). Metabolic syndrome has been found in approximately one quarter of the world’s population, and, despite the large-scale treatment, preventive and health-improving promotion programs on a global scale, the number of persons with MS tends to increase annually, especially among young ablebodied age. There are many risk factors in its genesis, including genetic predisposition, low physical activity, poor diet, smoking, intestinal microbiota, obstructive sleep apnea syndrome and others, the role of most of which needs to be studied in more depth. Many criteria have been proposed for the diagnosis of MS, each of them has its own advantages and disadvantages. With MS, most organs and systems are affected, and with the combined involvement of the cardiovascular, endocrine, urinary, digestive and respiratory systems burdened clinical course of MS. In connection with the above, there is a reason for further scientific research to identify the causes and risk factors for the development of MS, development of preventive ways of prevention, preventive diagnostics and early treatment of MS.

Keywords: metabolic syndrome, epidemiology, pathogenesis, diabetes mellitus, insulin resistance, obesity, hypercholesterolemia.

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Authors' information:

Abdullozoda Said Murtazo
Candidate of Medical Sciences, Applicant for the Department of Epidemiology, Avicenna Tajik State Medical University
ORCID ID: 0000-0003-0058-7633
SPIN: 5979-1928
Author ID: 991827
E-mail: saidxoja@gmail.com

Information about support in the form of grants, equipment, medications

The author did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:

Abdullozoda Said Murtazo
Candidate of Medical Sciences, Applicant for the Department of Epidemiology, Avicenna Tajik State Medical University

734003, Republic of Tajikistan, Dushanbe, Rudaki Ave., 139

Tel.: +992 (44) 6003659

E-mail: saidxoja@gmail.com

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