Literature Reviews

doi: 10.25005/2074-0581-2021-23-3-418-431
PERSONALISED MEDICINE IN BRONCHIAL ASTHMA: CURRENT CONCEPTS AND PROSPECTS

R.M. Fayzullina, V.V. Viktorov, R.R. Gafurova

Department of Faculty Pediatrics with Courses in Pediatrics, Neonatology and Simulation Center of IDPO, Bashkir State Medical University, Ufa, Russian Federation

Bronchial asthma (BA) is today a global medical and socio-economic issue in the health care system. Manifesting in childhood, the disease persists throughout the patient’s life, characterised by a variable clinical course. The periods of remission are combined with the periods of exacerbation and a wide range of symptoms ranging from mild symptoms to severe illness. Following the data of epidemiological studies, BA occupies a leading place among the chronic disorders of the lungs of non-infectious aetiology with increasing the annual prevalence trend. The article presents a literature review on the prospects for a personalised medicine (PM) approach for the group of socially significant, multifactorial diseases, including BA. Implementing PM for asthma patients makes it possible to diagnose and predict the disease even at the preclinical stage. This will reduce mortality, morbidity and disability rates, cut the costs of treatment and rehabilitation of symptomatic patients, and increase the patient’s adaptive capabilities, coping with outdoor environmental and local factors.

Keywords: Bronchial asthma, personalised medicine, HealthNet program, P4 medicine concept.

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Author information:


Fayzullina Rezeda Mansafovna
Doctor of Medical Sciences, Professor of the Department of Faculty Pediatrics with Courses in Pediatrics, Neonatology and Simulation Center of IDPO, Bashkir State Medical University
ORCID ID: 0000-0002-9001-1437
SPIN: 6706-3639
Author ID: 459354
E-mail: fayzullina@yandex.ru

Viktorov Vitaly Vasilyevich
Doctor of Medical Sciences, Full Professor, Head of the Department of Faculty Pediatrics with Courses in Pediatrics, Neonatology and Simulation Center of IDPO, Bashkir State Medical University
Researcher ID: B-8214-2018
ORCID ID: 0000-0001-5260-2319
SPIN: 4044-4161
Author ID: 288126
E-mail: surgped@bashgmu.ru

Gafurova Rita Rinatovna
Assistant of the Department of Faculty Pediatrics with Courses in Pediatrics, Neonatology and Simulation Center of IDPO, Bashkir State Medical University
ORCID ID: 0000-0001-9077-9780
SPIN: 3334-7890
Author ID: 1033519
Е-mail: rita.gafurova2017@yandex.ru

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from companies manufacturing medications and medical equipment

Conflicts of interest: No conflict

Address for correspondence:


Gafurova Rita Rinatovna
Assistant of the Department of Faculty Pediatrics with Courses in Pediatrics, Neonatology and Simulation Center of IDPO, Bashkir State Medical University

450008, Russian Federation, Republic of Bashkortostan, Ufa, Lenin str., 3

Tel. : +7 (937) 33233332

Е-mail: rita.gafurova2017@yandex.ru