FOR THE MEDICAL PRACTITIONER
Pediatric Surgery
doi: 10.25005/2074-0581-2024-26-3-452-460
PEDIATRIC UROLITHIASIS: PREDISPOSING FACTORS AND EARLY DIAGNOSIS IN OUTPATIENT SETTING

SH.A. YUSUPOV1, L.R. KHAKIMOVA2

1Department of Pediatric Surgery № 1, Samarkand State Medical University, Samarkand, Republic of Uzbekistan
2Department of General Practice/Family Medicine, Faculty of Continuing Professional Education, Samarkand State Medical University, Samarkand, Republic of Uzbekistan

Objective: To optimize the algorithm for early diagnosis of urolithiasis (UL) in children, considering risk factors, clinical and functional characteristics of the disease, and immunogenetic predisposition in an outpatient setting

Methods: The literature on managing children with UL outside the hospital was thoroughly analyzed to achieve the goal. Medical records, risk factors, including immunogenetic predisposition, and clinical and laboratory investigation results of 652 hospitalized children with UL were studied. Additionally, a retrospective study of 379 outpatient records (the control group) and a prospective study of 1275 children (the study group) aged 1 to 18 was conducted. Based on the outpatient records analysis, the effectiveness of current and optimized management algorithms for children with UL was compared

Results: As a result of the research, an algorithm for early diagnosis and prediction of UL in children, considering risk factors, including immunogenetic predisposition, was developed. The algorithm evaluates the risk of developing UL based on a thirteen-point checklist that assesses benefits and risks to provide a personalized risk score for each child. Based on this risk score, additional therapeutic interventions are determined for each patient

Conclusion: The algorithm developed for early diagnosis and prediction of UL in children helps identify the condition at a preclinical stage in an outpatient setting. This algorithm categorizes patients into low-, moderate-, or high-risk groups and guides their management accordingly

Keywords: Urolithiasis in children, early diagnosis, risk factors, prediction of urolithiasis, genetic factors, prelithiasis, outpatient service.

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Authors' information:

Yusupov Shukhrat Abdurasulovich,
Doctor of Medical Sciences, Associate Professor, Head of the Department of Pediatric Surgery № 1, Samarkand State Medical University
ORCID ID: 0000-0001-7259-028X
Author ID: 554847
SPIN: 3576-7390
E-mail: shuchrat_66@mail.ru

Khakimova Leyla Rafikovna,
Senior Lecturer, Department of General Practice/ Family Medicine, Faculty of Continuing Professional Education, Samarkand State Medical University
ORCID ID: 0000-0003-4638-9499
E-mail: lsf-3@rambler.ru

Information about support in the form of grants, equipment, medications

The work was carried out in accordance with the research plan of the Samarkand State Medical University "Development of advanced technologies for the prevention, diagnosis and treatment of socially significant human diseases of infectious and non-infectious etiology" (state registration number 012000260). The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:

Yusupov Shukhrat Abdurasulovich
Doctor of Medical Sciences, Associate Professor, Head of the Department of Pediatric Surgery № 1, Samarkand State Medical University

140100, Republic of Uzbekistan, Samarkand, Orzu str., 32

Tel.: +998 (915) 481613

E-mail: shuchrat_66@mail.ru

Materials on the topic:
  1. TREATMENT OF PERISTOMAL COMPLICATIONS IN CHILDREN WITH EXTERNAL ARTIFICIAL SMALL INTESTINE FISTULAS
  2. THE ROLE OF ULTRASOUND AND VIDEOLAPAROSCOPY IN DIAGNOSIS AND TREATMENT OF ACUTE SURGICAL DISEASES OF THE ABDOMINAL CAVITY ORGANS IN CHILDREN

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