Interventional Cardiology
doi: 10.25005/2074-0581-2025-27-3-651-663
THE LONG-TERM EFFICACY OF DIFFERENT ENDOVASCULAR TREATMENTS FOR CORONARY ARTERY CALCIFICATION FOLLOWED BY STENTING
North-Western State Medical University named after I.I. Mechnikov, Saint-Petersburg, Russian Federation
Objective: To evaluate the long-term efficacy of different methods of endovascular treatment of coronary artery calcification (CAC), followed by stenting.
Methods: Outpatient follow-up results were analyzed, and data regarding the long-term quality of life of patients in two groups were collected. Both groups received surgery between 2017 and the first half of 2022. The main group (MG) consisted of 71 patients who were treated with a combination of rotational atherectomy (RA) followed by angioplasty and stenting of the coronary arteries. Meanwhile, the control group (CG) included 138 patients who underwent standard balloon angioplasty with stenting. Both groups were matched in terms of gender distribution and age. In the MG, 59.2% of the patients were men and 40.8% were women. In the CG, these figures were 55.1% men and 44.9% women. Additionally, the average age was 72±6.9 years in the MG and 70±6.8 years in the CG. Both groups also had a high body mass index, indicating similar anthropometric parameters.
Results: The analysis of remote treatment results in both groups focused on several key indicators: long-term patient survival, recurrence of CAC, restenosis, occurrence of major adverse cardiovascular events (MACE), repeated surgical interventions (such as coronary artery bypass grafting and coronary stenting), and assessments of the patients' physical and mental well-being using the 36-Item Short Form Survey (SF-36). The findings indicated that patients in the TG experienced a statistically significant reduction in restenosis and MACE over the long term. Additionally, data showed a significantly higher level of mental and physical well-being in patients from the MG compared to those in the CG.
Conclusion: The use of RA resulted in lower rates of restenosis and MACE during the remote follow-up period when compared to CG. Additionally, MG patients demonstrated a higher quality of life in both physical and psychological aspects. Therefore, it is recommended to increase the use of RA in the endovascular treatment of CAC conditions.
Keywords: Coronary artery calcification, endovascular treatment, long-term results, rotational atherectomy, balloon angioplasty, restenosis.
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Authors' information:
Fedorov Artyom Sergeevich,
Doctor for X-ray Endovascular Diagnostics and Treatment in the cathlab, as part of the Department of X-ray Surgical Methods of Diagnosis and Treatment of the Peter the Great Clinic, North-Western State Medical University named after I.I. Mechnikov
ORCID ID: 0000-0001-8608-3238
E-mail: Artem.Fedorov@szgmu.ru
Shishkevich Andrey Nikolaevich,
Doctor of Medical Sciences, Associate Professor of the Department of Cardiovascular Surgery, North-Western State Medical University named after I.I. Mechnikov
ORCID ID: 0000-0003-4605-6678
E-mail: shishkevich50@mail.ru
Kravchuk Vyacheslav Nikolaevich,
Doctor of Medical Sciences, Full Professor, Head of the Department of Cardiovascular Surgery, North-Western State Medical University named after I.I. Mechnikov
ORCID ID: 0000-0002-6337-104X
E-mail: kravchuk9@yandex.ru
Asadulaev Shamil Magomedovich,
Doctor for X-ray Endovascular Diagnostics and Treatment in the cathlab, as part of the Department of X-ray Surgical Methods of Diagnosis and Treatment of the Peter the Great Clinic, North-Western State Medical University named after I.I. Mechnikov
ORCID ID: 0000-0002-1915-1250
E-mail: shamil.asadulaev@szgmu.ru
Porembskaya Olga Yaroslavna,
Candidate of Medical Sciences, Assistant of the Department of Cardiovascular Surgery, North-Western State Medical University named after I.I. Mechnikov
ORCID ID: 0000-0003-3537-7409
E-mail: porembskaya@yandex.ru
Umantsev Evgeniy Igorevich,
Doctor for X-ray Endovascular Diagnostics and Treatment in the cathlab, as part of the Department of X-ray Surgical Methods of Diagnosis and Treatment of the Peter the Great Clinic, North-Western State Medical University named after I.I. Mechnikov
ORCID ID: 0009-0005-4499-7257
E-mail: Dr.umancev@mail.ru
Muratbekova Umut Muratbekovna,
Postgraduate Student of the Department of Cardiovascular Surgery, North-Western State Medical University named after I.I. Mechnikov
ORCID ID: 0009-0009-9854-9838
E-mail: umutmurat.kg@gmail.com
Information about support in the form of grants, equipment, medications
The authors did not receive financial support from manufacturers of medicines and medical equipment
Conflicts of interest: No conflict
Address for correspondence:
Fedorov Artyom Sergeevich
Doctor for X-ray Endovascular Diagnostics and Treatment in the cathlab, as part of the Department of X-ray Surgical Methods of Diagnosis and Treatment of the Peter the Great Clinic, North-Western State Medical University named after I.I. Mechnikov
191015, Russian Federation, Saint-Petersburg, Kirochnaya str., 41
Tel.: +7 (911) 1938659
E-mail: Artem.Fedorov@szgmu.ru
This work is licensed under a Creative Commons Attribution 4.0 International License.
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