Obstetrics and Gynecology
doi: 10.25005/2074-0581-2017-19-2-142-146
COURSE OF PREGNANCY IN WOMEN WITH VARICOSE DISEASE

M.M. Marizoeva1, O. Nematzoda2, D.D. Sultanov2, 3, G.O. Nazirova1, U.S. Ismatova1, O.B. Bobdzhonova3

1Local Maternity Hospital № 2, Health Department of Khukumat of Dushanbe City, Dushanbe, Tajikistan
2Republican Scientific Center for Cardiovascular Surgery, Dushanbe, Tajikistan
3Avicenna Tajik State Medical University, Dushanbe, Tajikistan

Objective: Evaluation of the influence of varicose disease on the course and outcome of pregnancy.

Methods: A comparative analysis of the pregnancy course was carried out in 24 women with varicose disease (the main group) and 24 pregnant women without it (control group). Both groups for age and pregnancy were comparable. The average age of women in both groups was 27.2± 3.1 years. Criteria of exceptions from the groups were preeclampsia and concomitant severe extragenital diseases. According to the clinical classification of CEAP, 20 patients had clinical grade II (C2), in 4 patients – clinical class III (C3) of chronic venous insufficiency. The combined varicose veins of great saphenous vein and its inflows, the veins of the vulva and the vagina were noted in 10 (41.7%) patients, isolated expansion of the trunk of the great saphenous vein and its inflows in 12 (50%) pregnant women, and pelvic congestion syndrome, dilatation of great saphenous vein and veins of the external genitals – in 2 (8.3%) cases.

Results: At the end of the second trimester, 10 (41.7%) of the pregnant (main group) had dysuric disorders, whereas, in the control group only 1 (4.2%) observed these events. The incidence of placental insufficiency in patients of the main group (n = 12; 50%) was higher than in the control group (n = 1; 4.2%). The threat of interrupt pregnancy in the main group was registered in 14 (58.3%) cases, in the control group – only in 1 (4.2%) patients (p>0.05). The intrauterine growth retardation of a fetus was noted in 3 (12.5%) patients of the main group. In the main group, hydramnion were in 4 (16.7%) patients, whereas in the pregnant women of the control group, it occurred only in 1 (4.2%) cases (p> 0.05). In 4 (8.3%) patients of both groups, there was an edematous variant of gestosis, with a significant difference: in 3 (12.5%) patients in the main and in 1 (4.2%) control groups.

Conclusion: The varicose disease leads to an increase in the development of various severe complications of gestation, which requires a comprehensive and timely correction.

Keywords: pregnancy, varicose veins, threat interruption of pregnancy, intrauterine growth retardation of fetus, outcomes.

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Authors' information:

Marizoeva Mahina Mahmadulloevna,
Doctor, the obstetrician-gynecologist of the Local Maternity Hospital № 2 of the Dushanbe City Health Department

Nematzoda Okiljon,
Candidate of Medical Sciences, Leading Researcher of the State Institution "Republican Scientific Center for Cardiovascular Surgery"

Sultanov Javli Davronovich,
Doctor of Medical Sciences, Full Professor, Head of the Department of Science of State Institution "Republican Scientific Center for Cardiovascular Surgery", Professor of the Department of Surgical Diseases № 2, Avicenna Tajik State Medical University

Nazirova Gulnora Obidovna,
Doctor, the obstetrician-gynecologist of the Local Maternity Hospital № 2 of the Dushanbe City Health Department

Ismatova Umiya Subhonovna,
Doctor, the obstetrician-gynecologist of the Local Maternity Hospital № 2 of the Dushanbe City Health Department

Bobdzhonova Oksana Bobdzhonovna,
The Clinical Resident of the Department of Obstetrics and Gynecology№ 2, Avicenna Tajik State Medical University

Conflicts of interest: No conflict

Address for correspondence:

Nematzoda Okiljon

Candidate of Medical Sciences, Leading Researcher of the State Institution "Republican Scientific Center for Cardiovascular Surgery"

734003, Republic of Tajikistan, Dushanbe, Sanoi street, 33

Tel.: (+992) 915 250055

E-mail: sadriev_o_n@mail.ru

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