Epidemiology
doi: 10.25005/2074-0581-2019-21-2-285-290
EPIDEMIOLOGICAL ANALYSIS OF MEASLES OUTBREAK IN KYRGYZ REPUBLIC FOR THE 2018 YEAR

M.S. Niyazalieva1, Zh.T. Isakova2, V.S. Toygombaeva2, E.Zh. Zholdoshbekov3

1Department of Microbiology, Virology, and Immunology, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, Kyrgyz Republic
2Department of General and Clinical Epidemiology, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, Kyrgyz Republic
3Department of Faculty Surgery, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, Kyrgyz Republic

Objective: To analyze the development of the measles outbreak in 2018 among the population of the Kyrgyz Republic to improve the prevention system in the country.

Methods: An operational and retrospective epidemiological analysis of official statistics has been carried out. The diagnosis of measles was confirmed with the immunoenzyme analysis (IEA) using the Vector-Best IgM Measles n-905 test system. The genotype of the measles virus was determined in the laboratory of the Moscow Research Epidemiology and Microbiology Institute named after G.N. Gabrichevsky, the material served as nose-swallow scrape and urine.

Results: A total of 1,005 cases of measles have been reported in the country (an intensive indicator of 16,10/0000), of which 515 have been laboratoryconfirmed and 490 cases have been clinically and epidemiologically interconnected. The areas of risk were Bishkek with an incidence rate of 57.2% and Chui region – 24.5%. Risk groups were children under the year of life – 45.7% and at the age of 1-4 years – 37.1 %. Risk time is spring-summer and autumn periods. The main proportion of patients were unvaccinated – 92%, of which 45% were children under the year, 21% – due to failures, 11% – with medical recusals and 5% – due to migration of the population.

Conclusion: The presence of non-immune stratum among the population, formed by the causes of frequent failures, migration of the population and medical recusals, as well as in the conditions of the emergence of hospital-acquired hotbeds in the infectious and non-infectious hospitals have contributed to the outbreak of measles in Kyrgyzstan among the young children.

Keywords: Measles, outbreak, morbidity, virus genotype, immunization, vaccination status.

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Authors' information:

Niyazalieva Mira Suerkulovna
, Candidate of Medical Sciences, Associate Professor of the Department of Microbiology, Virology and Immunology, I.K. Akhunbaev Kyrgyz State Medical Academy

Isakova Zhaynagul Turganbaevna
, Candidate of Medical Sciences, Assistant of the Department of General and Clinical Epidemiology, I.K. Akhunbaev Kyrgyz State Medical Academy

Toygombaeva Vera Sadvakasovna
, Doctor of Medical Sciences, Full Professor, Head of the Department of General and Clinical Epidemiology, I.K. Akhunbaev Kyrgyz State Medical Academy

Zholdoshbekov Esengeldi Zholdoshbekovich
, Doctor of Medical Sciences, Professor of the Department of Faculty Surgery, I.K. Akhunbaev Kyrgyz State Medical Academy

Conflicts of interest: No conflict

Address for correspondence:

Niyazalieva Mira Suerkulovna
Candidate of Medical Sciences, Associate Professor of the Department of Microbiology, Virology and Immunology, I.K. Akhunbaev Kyrgyz State Medical Academy

720020, Kyrgyz Republic, Bishkek, Akhunbaev Street, 92

Tel.: +996 (772) 140412

E-mail: niyazalieva_mira@mail.ru

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