Obstetrics and Gynecology
doi: 10.25005/2074-0581-2019-21-3-374-379
REPRODUCTIVE FUNCTION OF WOMEN WITH THE HISTORY OF DIFFUSE APPENDICULAR PERITONITIS IN CHILDHOOD

A.M. Shamsiev, Sh.A. Yusupov

Department of Pediatric Surgery, Samarkand State Medical Institute, Samarkand, Republic of Uzbekistan

Objective: To study the reproductive function of women in the long-term period after surgical treatment of diffuse appendicular peritonitis (DAP) in childhood.

Methods: From the 163 operated girls fertility function was studied in 115 in the long-term period, including 62 patients in the control group and 53 in the main group. In the main group, intra-operative abdominal ozone therapy was used to prevent adhesive process; introduction of ozone-oxygen mixture through micro-irrigator and ultra-phonophoresis or electrophoresis on the anterior abdominal wall in the early postoperative period.

Results: It has been established that the history of DAP in childhood was not reliably affected the cyclicality of the menstrual cycle in a long-term period, although there was a decrease in the frequency of this indicator to the main group to 15.1% compared to the control group – 27.4% (p>0.05). In relation for painful menstruation, the difference between groups was statistically significant (18.9% vs. 38.7%, p<0.05). In addition, in the control group more than twice as often cases of ectopic pregnancies, miscarriages and premature births were registered (48.4% vs. 22.6%, p<0.05) and infertility was more common (29.0% vs. 13.2%, р<0.05). Of the 25 women with infertility who suffered from DAP in childhood, 23 were underwent hysterosalpingography. At the same time, against the background of the normal hormonal status tubal-peritoneal form of infertility was diagnosed associated with the adhesive process in the small pelvis. At 11 (47.8%) observations occlusion of fallopian tubes occurred, and in 10 of them the process was right-handed

Conclusion: Improving the comprehensive treatment of children with DAP has significantly reduced its negative impact on the reproductive system of girls.

Keywords: Appendicular peritonitis, complications, girls, reproductive function, intra-operative ozone therapy, tubal infertility.

Download file:

References
  1. Yusupov ShA. Diagnostika vnutribryushnykh abstsessov v rannem posleoperatsionnom periode pri appendikulyarnykh peritonitakh u detey [Diagnosis of intra-peritoneal abscess of post operation period among children with appendicular peritonitis]. Vestnik Ural’skoy meditsinskoy akademicheskoy nauki. 2009;3:36-9.
  2. Burlev VA, Dubinskaya ED, Gasparov AS. Peritoneal’nye spayki ot patogeneza do profilaktiki [Peritoneal adhesions from pathogenesis to prophilaxis]. Problemy reproduktsii. 2009;15(3):36-44.
  3. Adamou H, Habou O, Amadou-Magagi I, Doutchi M, Amadou M, Halidou M. Non-traumatic acute peritonitis in children: causes and prognosis in 226 patients at the National Hospital of Zinder, Niger. Med Sante Trop. 2017;27(3):264-9. Available from: https://doi.org/10.1684/mst.2017.0692.
  4. Makarov АB, Dergunov AV. Osobennosti patogeneza i printsipy patogeneticheskoy terapii endogennoy intoksikatsii u bol’nykh s ostrym appendikulyarnym peritonitom [Features of pathogenesis and principles of pathogenic therapy of edogenous intoxication in patients with acute appendicular peritonitis]. Rossiyskiy mediko-biologicheskiy vestnik im. akademika I.P. Pavlova. 2009;17(3):105-13.
  5. Burlev VA, Dubinskaya ED. Fenotipicheskie osobennosti nedifferentsirovannykh form displazii soedinitel’noy tkani u patsientok s tazovymi peritoneal’nymi spaykami [Phenotypic characteristics of undifferentiated connective tissue dysplasia in patients with pelvic peritoneal adhesions]. Problemy reproduktsii. 2012;18(2):8-14.
  6. Gavrilyuk VP. Kliniko-immunologicheskaya effektivnost’ longidazy u detey s appendikularnym peritonitom [Clinical and immunological efficiency of longidaza at children with the appendicular peritonitis]. Vrach-aspirant. 2011;44(1):140-5.
  7. Dubinskaya E, Gasparov A, Nazarov S, Dorfman M. Sostoyanie reproduktivnoy sistemy bol’nykh s tazovymi peritoneal’nymi spaykami i besplodiem [The reproductive system in patients with pelvic peritoneal adhesions and infertility]. Vrach. 2010;7:43-5.
  8. Abashidze AA. Metody reabilitatsii reproduktivnoy funktsii u zhenshchin s trubno-peritoneal’nym besplodiem [Rehabilitation methods of reproductive function in women with tubal-peritoneal infertility]. Medikosotsial’naya ekspertiza i reabilitatsiya. 2014;2:42-6.
  9. Fatkina OA, Sibirskaya EV, Poddubnyy IV, Glybina TM. Algoritm obsledovaniya i lecheniya devochek s appendikulyarno-genital’nym sindromom [Algorithm of diagnosis and treatment of girls with appendicular and genital syndrome]. Problemy reproduktsii. 2014;20(1):33-40.
  10. Ben Salkha M, Repina NB, Dmitrieva MN. Metody diagnostiki posleoperatsionnogo spaechnogo protsessa v malom tazu u zhenshchin s khronicheskoy tazovoy bol’yu na fone nedifferentsirovannoy displazii [Diagnosis of postoperative pelvic adhesions in women with chronic pelvic pain on the background of undifferentiated connective tissue dysplasia]. Vestnik Avitsenny [Avicenna Bulletin]. 2018;20(1):13-9. Available from: https://doi.org/10.25005/2074-0581-2018-20-1-13-19.
  11. Yusupov Sh. Assessment of the effectiveness of ultrasound sonography among children with appendicular peritonitis. European sciences review. 2017;1-2:161-3. Available from: https://doi.org/10.20534/ESR-17-1.2-161- 163.
  12. Dabuzov ASh, Abdurakhmanova RA, Medzhidova DR. Iskhody gestatsii posle organosokhranyayushchikh operatsiy, provedyonnykh po povodu peritonita v anamneze [Outcomes of gestation after organ-saving surgery, performed for peritonitis]. Sovremennye problemy nauki i obrazovaniya. 2015;6. URL: http://science-education.ru/ru/article/view?id=23750 [Accessed 10th September 2019].
  13. Amerkhanova KhS, Tsallagova LV, Kabulova IV. Rezul’taty spetsial’nykh metodov obsledovaniya patsientok s trubno-peritoneal’noy formoy besplodiya [The results of special methods of examination of patients with tubal-peritoneal form of infertility]. Problemy reproduktsii. 2019;25(1):26- 30. Available from: https://doi.org/10.17116/repro20192501126.

Authors' information:

Shamsiev Azamat Mukhitdinovich
Doctor of Medical Sciences, Professor of the Department of Pediatric Surgery, Rector of the Samarkand State Medical Institute
ORCID ID: 0000-0001-9282-5795
E-mail: samgmi@mail.ru

Yusupov Shukhrat Abdurasulovich
Doctor of Medical Sciences, Associate Professor, Head of the Department of Pediatric Surgery, Vice-Rector for Science and Innovation, Samarkand State Medical Institute
ORCID: 0000-0001-7259-028X
E-mail: shuchrat_66@mail.ru

Information about support in the form of grants, equipment, medications

The work was carried out according to the plan of scientific research works of Samarkand State Medical Institute (state registration number – 01.001195). The authors did not receive financial support from manufacturers of medicines and medical equipment.

Conflicts of interest: No conflict

Address for correspondence:

Yusupov Shukhrat Abdurasulovich
Doctor of Medical Sciences, Associate Professor, Head of the Department of Pediatric Surgery, Vice-Rector for Science and Innovation, Samarkand State Medical Institute

140100, Republic of Uzbekistan, Samarkand, 18 Amir Temur str

Tel.: + 998 (915) 481613

E-mail: shuchrat_66@mail.ru

Materials on the topic:
  1. PREMATURE SEPARATION OF THE NORMALLY IMPLANTED PLACENTA
  2. MORPHOFUNCTIONAL FEATURES OF THE PLACENTA IN PREGNANT WOMEN WITH TUBERCULOSIS
  3. INDUCTION OF LABOR IN PRE-ECLAMPTIC WOMEN
  4. EMERGENCY CESAREAN SECTION WITH REDO MITRAL VALVE REPLACEMENT FOR ACUTE PROSTHETIC VALVE DYSFUNCTION: A CASE REPORT
  5. MODERN CONCEPTS OF VOMITING OF PREGNANCY
  6. EPIDEMIOLOGY AND RISK FACTORS FOR MATERNAL SEPSIS
  7. FOLATE METABOLISM IN PREGNANCY
  8. Reserves for improving perinatal indicators by analyzing the outcomes of preterm labor
  9. ASSESSMENT OF THE UFS-QOL QUESTIONNAIRE BEFORE AND AFTER UTERINE ARTERY EMBOLIZATION FOR UTERINE LEIOMYOMA
  10. CHARACTERISTICS OF SOME OBSTETRIC AND GYNECOLOGICAL FEATURES IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME AND CONCOMITANT THYROID GLAND PATHOLOGY

◄ Back to the list