REVIEW ARTICLE
Cardiology
doi: 10.25005/2074-0581-2025-27-3-695-702
CORONARY ARTERY ECTASIA: CURRENT CONCEPTS

М.KH. DADABAEV1,2, Z.Т. RADZHAPOVA3, Т.М. MURATALIEV1,4, ZH.А. OTKEEVA4

1Department of Cardiac Surgery and Endovascular Surgery, Kyrgyz State Medical Academy named after I.K. Akhunbaev, Bishkek, Republic of Kyrgyzstan
2Department of Endovascular Diagnostic and Treatment Methods, National Center of Cardiology and Internal Medicine named after Academician Mirsaid Mirrakhimov, Bishkek, Republic of Kyrgyzstan
3Department of Therapy No. 2 Specialty “General Medicine”, Medical Faculty of the Kyrgyz-Russian Slavic University named after the first President of the Russian Federation B.N. Yeltsin, Bishkek, Republic of Kyrgyzstan
4Department of Ischemic Heart Disease, National Center of Cardiology and Internal Medicine named after Academician Mirsaid Mirrakhimov, Bishkek, Republic of Kyrgyzstan

Coronary artery ectasia (CAE) is a rare condition that affects 3-8% of patients with coronary artery disease (CAD), characterized by abnormal dilation of the arteries. The etiology of CAE encompasses a range of acquired and genetic factors, and its pathogenesis remains a subject of ongoing research and debate. Clinical manifestations of CAE can vary widely, ranging from asymptomatic cases to chronic or acute coronary syndrome (ACS). Currently, coronary angiography is considered the gold standard for CAE diagnosis.

Current research focuses on understanding the mechanisms underlying the development of CAE, assessing its clinical significance, and optimizing management approaches. There are no universally accepted therapeutic strategies, which underscores the need for an individualized approach to treatment. The risks of thrombosis, ischemia, and disease progression highlight the significance of contemporary diagnostics and monitoring of CAE. Despite being described over 50 years ago, the etiopathogenesis and management tactics for patients with CAE remain topics of ongoing discussion. To this end, we reviewed the literature from the past decade, utilizing databases such as PubMed and Google Scholar. We used keywords including "coronary artery ectasia", "etiopathogenesis", "clinical presentation", "diagnostics", and "treatment", either separately or in combination. Our review centered on the etiopathogenesis, clinical presentation, diagnosis, and treatment of CAE.

Keywords: Coronary artery ectasia, etiopathogenesis, clinical features, diagnostics, treatment.

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Authors' information:

Dadabaev Murat Khasanovich,
Doctor of Medical Sciences, Full Professor, Head of the Department of Cardiac Surgery and Endovascular Surgery, Kyrgyz State Medical Academy named after I.K. Akhunbaev; Head of the Department of Endovascular Diagnostic and Treatment Methods, National Center of Cardiology and Internal Medicine named after Academician Mirsaid Mirrakhimov
Scopus ID: 6505797380
ORCID ID: 0000-0001-5825-2866
Author ID: 3077667
E-mail: dadmed@mail.ru

Radzhapova Zulfiya Tulkunovna,
Candidate of Medical Sciences, Associate Professor of the Department of Therapy No. 2 Specialty “General Medicine”, Medical Faculty of the Kyrgyz-Russian Slavic University named after the first President of the Russian Federation B.N. Yeltsin
Researcher ID: O-5138-2015
Scopus ID: 57191867631
ORCID ID: 0000-0002-8255-0473
SPIN: 8789-1025
Author ID: 965378
E-mail: mztzmr@gmail.com

Murataliev Tulkun Muratalievich,
Doctor of Medical Sciences, Full Professor, Professor of the Department of Cardiac Surgery and Endovascular Surgery, Kyrgyz State Medical Academy named after I.K. Akhunbaev; Consulting Professor of the Department of Ischemic Heart Disease, National Center of Cardiology and Internal Medicine named after Academician Mirsaid Mirrakhimov
Researcher ID: R-2166-2017
Scopus ID: 6602708387
ORCID ID: 0000-0003-2281-8199
SPIN: 7171-4904
Author: 389675
E-mail: murataliev@mail.ru

Otkeeva Zharkyn Akylbekovna,
Cardiologist of the Department of Ischemic Heart Disease, National Center of Cardiology and Internal Medicine named after Academician Mirsaid Mirrakhimov
ORCID ID: 0009-0001-0190-2351
SPIN: 9222-7033
E-mail: zh.otkeeva94@gmail.com

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The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:

Radzhapova Zulfiya Tulkunovna
Candidate of Medical Sciences, Associate Professor of the Department of Therapy No. 2 Specialty “General Medicine”, Medical Faculty of the Kyrgyz-Russian Slavic University named after the first President of the Russian Federation B.N. Yeltsin

720000, Republic of Kyrgyzstan, Bishkek, Kiev str., 44

Tel.: +996 (559) 344660

E-mail: mztzmr@gmail.com


This work is licensed under a Creative Commons Attribution 4.0 International License.

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