doi: 10.25005/2074-0581-2018-20-2-3-202-206

B.A. Akmatova

Department of Infectious Diseases, HIV/AIDS and Dermatovenereology, Kyrgyz State Medical Institute for Retraining and Advanced Studies, Bishkek, Kyrgyz Republic

Objective: Assessment of services to detect and diagnose of tuberculosis (TB) people living with HIV (PLHIV).

Methods: Service evaluation conducted on four sites attracted in this study. Conducted semi-structured interviews in small groups with staff (32 people) and 20 PLHIV (including 7 patients with TB/HIV) aged 28-59 years; analysis of retrospective program monitoring data from the electronic tracking system (ETS) for cases of HIV infection for the year 2015. Data analysis of the survey of PLHIV carried out with the help of the EpiInfo program. The data interviews of key partners and medical staff were grouped by topics. The data of the ETS adjusted from the medical records of the patients. The extraction of data from the ETS system was carried out in an impersonal and aggregated form. The study design is convergent.

Results: The percentage of PLHIV who have undergone clinical screening for tuberculosis during their last visit ranges from 57% to 79%, and among PLHIV who use injecting drugs, 67% to 83%. The percentage of PLHIV who underwent X-ray examination in 2015 ranged from 53% to 96%, and among PLHIV using injecting drugs, from 52% to 94%. The process of diagnosing tuberculosis in PLHIV is sometimes delayed due to a number of barriers preventing modern collections of services for tuberculosis.

Conclusion: Close cooperation and continuity between the TB service, AIDS services and primary health care to allow improved the detection and diagnosis of tuberculosis in PLHIV.

Keywords: Tuberculosis, HIV infection, people living with HIV, interview, clinical screening for tuberculosis.

Download file:

  1. Getahun H, Gunneberg C, Granich R, Nunn P. HIV infection-associated tuberculosis: the epidemiology and the response. Clinical Infectious Diseases. 2010;50(3):201-7. Available from: pubmed/20397949.
  2. Bruce RD, Lambdin B, Chang O, Masao F, Mbwambo J, Mteza I, et al. Lessons from Tanzania on the integration of HIV and tuberculosis treatments into methadone assisted treatment. International Journal of Drug Policy. 2014;25(1):22-5. Available from: 24210295.
  3. Tsinzerling VA, Svistunov VV. Tuberkulyoz v sochetanii s VICH-infektsiey: kliniko-morfologicheskie aspekty [Tuberculosis concurrent with HIV infection: clinical and morphological aspects]. Tuberkulyoz i bolezni lyogkikh. 2014;6:56-60.
  4. Bogorodskaya EM, Sinitsyn MV, Belilovsky EM, Borisov SE, Kotova EА. Vliyanie VICH-infektsii na strukturu vpervye vyyavlennykh bol’nykh tuberkulyozom, zaregistrirovannykh v gorode Moskve [Impact of HIV infection on the structure of new tuberculosis cases detected in the city of Moscow]. Tuberkulyoz i bolezni lyogkikh. 2017;10:17-26.
  5. Petersen E, Blumberg L, Wilson ME, Zumla A. Ending the global tuberculosis epidemic by 2030 – the Moscow declaration and achieving a major translational change in delivery of TB healthcare. International Journal of Tuberculosis and Lung Disease. 2017;65:156-8. Available from:
  6. Charalambous S, Grant AD, Innes C, Hoffmann CJ, Dowdeswell R, Pienaar J, et al. Association of isoniazid preventive therapy with lower early mortality in individuals on antiretroviral therapy in a workplace programme. AIDS. 2010;24(5):5-13. Available from: 21079429.
  7. Hoffmann CJ, Variava E, Rakgokong M, Masonoke K, van der Watt M, Chaisson RE, et al. High prevalence of pulmonary tuberculosis but low sensitivity of symptom screening among HIV-infected pregnant women in South Africa. PLoS One. 2013;8(4):e62211. Available from: https: // pubmed/23614037.
  8. Creswell J, Khowaja S, Codlin A, Hashmi R, Rasheed E, Khan M, et al. An evaluation of systematic tuberculosis screening at private facilities in Karachi, Pakistan. PLoS One. 2014;9(4):e93858. Available from: https: //www.
  9. Menberu MA. Performance of the WHO 2011TB symptom screening algorithm for pulmonary TB diagnosis among HIV-infected patients in Gondar University Referral Hospital, Ethiopia. International Journal of Microbiology. Volume 2016, Article ID 9058109, 5 pages. Available from:
  10. Kancheya N, Luhanga D, Harris JB, Morse J, Kapata N, Bweupe M, et al. Integrating active tuberculosis case finding in antenatal services in Zambia. International Journal of Tuberculosis and Lung Disease. 2014;18(12):1466-72. Available from: CD012934/full.
  11. Modi S, Cavanaugh JS, Shiraishi RW, Alexander HL, McCarthy KD, Burmen B, et al. Performance of clinical screening algorithms for tuberculosis intensified case finding among people living with HIV in Western Kenya. PLoS One. 2016;11(12):e0167685. Available from: https: // pubmed/27936146.
  12. LaCourse SM, Cranmer LM, Matemo D, Kinuthia J, Richardson BA, John-Stewart G, et al. Tuberculosis case finding in HIV-infected pregnant women in Kenya reveals poor performance of symptom screening and rapid diagnostic tests. Journal of Acquired Immune Deficiency Syndromes. 2016;71(2):219-27. Available from: CD012934/full.
  13. Broughton E, Haumba S, Calnan M, Ginindsa S, Jeffries R, Maphalala G, et al. Screening in Maternity to Ascertain Tuberculosis Status (SMATS) study. BMC Infect Dis. 2017;17(1):191. Available from:
  14. Swindells S, Komarow L, Tripathy S, Cain KP, MacGregor RR, Achkar JM, et al. Screening for pulmonary tuberculosis in HIV-infected indi-viduals: AIDS Clinical Trials Group Protocol A5253. Int J Tuberc Lung Dis. 2013;17(4):532-9. Available from: https: // / PMC 3923622.
  15. Kadyrov AS. Epidemiologicheskaya situatsiya po tuberkulyozu v Kyrgyzskoy Respublike v 2012-2016 godakh [Epidemiological situation on tuberculosis in the Kyrgys Republic in 2012-2016]. Nauka, novye tekhnologii i innovatsii Kyrgyzstana. 2017;8:3-7.

Authors' information:

Akmatova Begayym Akbagyshovna,
Candidate of Medical Sciences, Acting Associate Professor of the Department of Infectious Diseases, HIV/AIDS and Dermatovenereology, Kyrgyz State Medical Institute for Retraining and Advanced Studies

Conflicts of interest: No conflict

Address for correspondence:

Akmatova Begayym Akbagyshovna

Candidate of Medical Sciences, Acting Associate Professor of the Department of Infectious Diseases, HIV/AIDS and Dermatovenereology, Kyrgyz State Medical Institute for Retraining and Advanced Studies

720010, Kyrgyz Republic, Bishkek, Moscovskaya str., 221-22

Tel.: (+996) 555 337778


Materials on the topic: