Pharmacology
doi: 10.25005/2074-0581-2022-24-1-66-84
ANALYSIS OF ANTIBACTERIAL AND FUNGICIDAL ACTIVITY OF ALLIUM OSHANINII AND ALLIUM SUWOROWII DEPENDING ON THE ALTITUDE OF PLANT GROWTH

F.D. Mirzoeva

Department of Microbiology, Immunology and Virology, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan

Objective: To study the biological properties of plants of the genus Allium and their correlation with antimicrobial and fungicidal activity depending on the altitude of plant growth.

Methods: Seeds, leaves and bulbs of widespread wild and endemic species of the genus Allium growing in various regions of the Republic of Tajikistan were the objects of the study. The antimicrobial activity of the obtained extracts was studied against standard museum microorganisms (test strains): Staphylococcus aureus (ATCC 4929), Pseudomonas aeruginosa (ATCC 4930), Klebsiella pneumoniae (ATCC 4927), Escherichia coli (ATCC 4928). Antifungal activity was studied against Candida species.

Results: Correlation of varying strength was discovered between the content of biocomponents with antimicrobial and fungicidal activity, the altitude of plant growth and place of its collection. The content of total polyphenols and the antioxidant activity of extracts obtained from various parts of the plants varied over a wide range. In some cases, there were direct correlations of varying strength between the content of polyphenols, antioxidative, antimicrobial and fungicidal properties of the plants.

Conclusion: This study showed the insignificant correlations between the content of biocomponents and antimicrobial, and fungicidal properties of the studied types of onions, which did not depend on the growing zone.

Keywords: Onion, plant, growth inhibition, extract, reference bacterial strains.

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Authors' information:

Mirzoeva Fazila Davlatalievna
Acting Head of the Department of Microbiology, Immunology and Virology, Avicenna Tajik State Medical University
ORCID ID: 0000-0003-0187-0334
E-mail: fazila.mirzoeva88@mail.ru

Information about support in the form of grants, equipment, medications

The author did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:

Mirzoeva Fazila Davlatalievna Acting Head of the Department of Microbiology, Immunology and Virology, Avicenna Tajik State Medical University

Acting Head of the Department of Microbiology, Immunology and Virology, Avicenna Tajik State Medical University

734003, Republic of Tajikistan, Dushanbe, Rudaki Ave., 139

Tel.: +992 (919) 192191

E-mail: fazila.mirzoeva88@mail.ru

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