Oncology
doi: 10.25005/2074-0581-2022-24-4-463-470
COMPLEX DIAGNOSIS OF CERVICAL INTRAEPITHELIAL NEOPLASIA IN THE REPUBLIC OF TAJIKISTAN

N.A. Mukhsinzoda1, S.G. Umarova2

1Republican Cancer Research Center, Dushanbe, Republic of Tajikistan
2Department of Oncology and Radiation Diagnostics, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan

Objective: To study the experience of a comprehensive diagnosis of cervical intraepithelial neoplasia (CIN) based on the results of the first pilot visual screening in the Republic of Tajikistan.

Methods: The first pilot visual screening in two large districts of the Republic of Tajikistan was carried out in 2016. A total of 68,391 women of the target groups took part in this study, of which 26,691 (39%) were from the Kushoniyon district and 41,700 (61%) from the B. Gafurov district. According to the algorithm of organized visual screening, extended colposcopy, cytological examination, and biopsy with histological examination were performed.

Results: According to the results of the tests performed, in 164 cases (0.24%) CIN was diagnosed, while in 20 cases (0.03%) cervical cancer (CC) was detected (p<0.001). Mild low-grade squamous intraepithelial lesions (LSIL) lesions were detected in 99 cases (70 women from B. Gafurov district and 29 patients from Kushoniyon district), while severe high-grade squamous intraepithelial lesions (HSIL) were detected in 65 cases (59 women from B. Gafurov district and 6 women from Kushoniyon district). Patients with histologically confirmed precancerous pathology and cervical cancer were referred for outpatient and inpatient treatment.

Conclusion: The strategy of organized visual screening "detection-diagnosis-treatment", recommended by WHO for countries with limited resources, is optimal for implementation in the conditions of the Republic of Tajikistan at the national level.

Keywords: Cervical intraepithelial neoplasia, visual screening, VIA/VILI visual method, colposcopy.

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Authors' information:

Mukhsinzoda Nilufar Abdukakhkhorovna
Oncogynecologist, Department of Reproductology, Republican Cancer Research Center
ORCID ID: 0000-0002-8285-9091
SPIN: 6837-6437
Author ID: 1135265
E-mail: Nilufar.Abdugaffarova@mail.ru

Umarova Saida Gayratovna
Doctor of Medical Sciences, Professor of the Department of Oncology and Radiation Diagnostics, Avicenna Tajik State Medical University
ORCID ID: 0000-0002-5795-7503
SPIN: 4808-1066
Author ID: 1062229
E-mail: saida.umarova@bk.ru

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:

Mukhsinzoda Nilufar Abdukakhkhorovna
Oncogynecologist, Department of Reproductology, Republican Cancer Research Center

734025, Republic of Tajikistan, Dushanbe, Abuali Sino str., 58

Tel.: +992 (777) 002135

E-mail: Nilufar.Abdugaffarova@mail.ru

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