CASE REPORT
Oncology
doi: 10.25005/2074-0581-2024-26-4-694-699
CLINICAL CASE OF BCLC STAGE B HEPATOCELLULAR CARCINOMA WITH A COMBINED TREATMENT

A.I. ZAGORULKO1,2, M.R. ROZYEVA1, M.V. CHERNYAEV1

1RUDN University, Moscow, Russian Federation
2Cancer Center № 1, City Clinical Hospital named after S.S. Yudin, Moscow, Russian Federation

The article presents a clinical case of successful treatment of a patient with a BCLC stage B hepatocellular carcinoma (HCC), with the initial prediction of unfavorable radical treatment results and poor outcomes. The described approach allows the achievement of better results in patients with delayed treatment of HCC diagnosed at the advanced stage of the disease. A 69-year-old patient with pain and severe weakness was admitted to the hospital, where, according to the results of instrumental examination methods, a hepatic tumor was detected, qualified as HCC T3N0M0, stage II. Given the size and location of the tumor, combined treatment was performed, including two sessions of transarterial chemoembolization (TACE) with doxorubicin, targeted therapy with lenvatinib, microwave ablation, and surgical resection of the tumor. As a result, a progressive decrease in the tumor size was achieved with its subsequent radical removal and improved quality of life. The presented clinical case has shown that specialized care of HCC patients with advanced stages of the disease may be successful, and the accumulation of relevant experience may improve the quality and effectiveness of treatment for this group of patients.

Keywords: Hepatocellular carcinoma, transarterial chemoembolization, BCLC B stage, combined therapy, clinical case.

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References
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Authors' information:

Zagorulko Aleksey Ivanovich,
Candidate of Medical Sciences, Head of the Department of Endovascular Methods of Diagnosis and Treatment, Cancer Center № 1, City Clinical Hospital named after S.S. Yudin
ORCID ID: 0009-0000-9735-8073
SPIN: 5092-7397
E-mail: alexrus80@yandex.ru

Rozyeva Makhri Rakhimovna,
Student, RUDN University
Researcher ID: KEJ-4164-2024
ORCID ID: 0009-0007-1840-1039
E-mail: mehrirozyeva64@gmail.com

Chernyaev Mikhail Viktorovich,
Candidate of Medical Sciences, Assistant of the Department of Hospital Surgery with a Course of Pediatric Surgery, RUDN University
ORCID ID: 0000-0003-4925-7475
SPIN: 1509-3248
E-mail: mikhailcherniaev@mail.ru

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:

Chernyaev Mikhail Viktorovich
Candidate of Medical Sciences, Assistant of the Department of Hospital Surgery with a Course of Pediatric Surgery, RUDN University

117198, Russian Federation, Moscow, Miklukho-Maklay str., 6

Tel.: +7 (977) 5225353

E-mail: mikhailcherniaev@mail.ru


This work is licensed under a Creative Commons Attribution 4.0 International License.

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