Pediatrics
doi: 10.25005/2074-0581-2018-20-4-389-394
INDICES OF CENTRAL HEMODYNAMICS AND EXERCISE PERFORMANCE LEVEL IN CHILDREN WITH BRONCHIAL ASTHMA
Department of Pediatric Diseases № 2, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Objective: A comparative analysis of exercise performance and indices of central hemodynamics in children with bronchial asthma.
Methods: The results of the study of 40 children with bronchial asthma aged from 5 to 14 years are presented. The children were divided into 2 age groups: I – from 5 to 10 years old and II – from 11 to 14 years old. Along with general clinical research methods, the exercise performance was established by the PWC170 test. The following parameters of central hemodynamics were defined: minute volume of blood circulation (MVBC), cardiac index (CI), systolic blood volume (SBV), stroke volume (SV), heart rate (HR).
Results: It is established that in conditions of muscle rest in children with bronchial asthma, the indicators of MVBC and CI were higher than in healthy children, due to the greater heart rate. Such shifts hemodynamics observed at dosed physical loadings in children of both age groups, what indicates the reduction of the adaptive-compensatory capacity of the cardiovascular system.
Conclusion: A comprehensive study of the functional state of the cardiovascular system showed a significant decrease in physical performance in children with bronchial asthma. Almost all examined patients in both groups had an increase in MVBC due to heart rate. Such changes in hemodynamics were observed regardless of the age and duration of the disease, and during metered physical exertion (post load bronchospasm) – mainly during the post- and interracial periods of the disease.
Keywords: Bronchial asthma, children, central hemodynamics, exercise performance.
References
- Ismoilov KI, Sharipova MM. Strukturnoe i funktsional’noe sostoyanie u detey s bronkhial’noy astmoy [Struktural and functional state of cardiovascular system in children with asthma]. Vestnik Avitsenny [Avicenna Bulletin]. 2016;3:90-4.
- Markova TP, Kim MN. Osobennosti patogeneza i vrozhdyonnogo immuniteta pri bronkhial’noy astme [Features of pathogenesis and congenial immunity for bronchial asthma]. Pediatriya. 2016;95(4):110-5.
- Lai CKW, Beasley R, Crane J. Global variation in the prevalence end severity of asthma symptoms: phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax. 2009;64(6):476-83.
- Balabolkin II, Bulgakova VA. Bronkhial’naya astma u detey [Bronchial asthma in children]. Moscow, RF: OOO “Izdatel’stvo “Meditsinskoe informatsionnoe agenstvo”; 2015. 141 p.
- Balabolkin II. Sovremennye podkhody k terapii bronkhial’noy astmy u detey [Moderns approaches to therapy of bronchial asthma in children]. Detskayа pulmonologiya. 2016;4:131-6.
- Baranov AA, Namazova-Baranova LS, Khaitov RM, Ilina NI, Kurbachyova OM, Novik GA, i dr. Federal’nye klinicheskie rekomendatsii po okazaniyu meditsinskoy pomoshchi detyam s bronkhial’noy astmoy [Federal clinical guidelines for the provision of medical care for children with bronchial asthma]. Moscow, RF: 2016. 33 p.
- Natsional’naya programma “Bronchial’naya astma u detey. Strategiya lecheniya i profilaktika” [The national program «Bronchial asthma in children. The strategy of treatment and prevention]: 4-e izd., pererab. i dop. Moscow, RF: Original-maket; 2012. 184 p.
- Burkhart PV. Children’s self-reports of characteristics of their asthma episodes: The Journal of Asthma. 2003;40:909-16.
- Denisova TV, Rychkova LV, Serikova AA. Funktsional’noe sostoyanie serdechnososudistoy sistemy i vegetativnyy gomeostaz u detey s bronkhial’noy astmoy [Functional state of the cardiovascular system and autonomic homeostasis in children with bronchial asthma]. Byulleten’ VSNTS SO RAMN. 2005;5:136-42.
- Eliseeva TI, Balabolkin II. Sovremennye tekhnologii kontrolya bronchial‘noy astmy u detey (obzor) [Modern technologies of bronchial asthma control in children (literature review)]. Sovremennye tekhnologii v meditsine. 2015;7(2):168-84.
- Gavrisyuk VN. Narusheniya serdechno-sosudistoy sistemy u bol’nykh bronkhial’noy astmoy [Violations of the cardiovascular system in patients with bronchial asthma]. Ukrainskiy pul’monologicheskiy zhurnal. 2000;2:45-9.
- Orlova AF, Leytes IV. Proby s fizicheskoy nagruzkoy. Metodicheskoe posobie po veloergometrii [Tests with physical exertion: Methodical manual on veloergometry]. Barnaul, RF: 2002. 55 p.
- Tavrovskaya TV. Veloergometriya. Practicheskoe posobie dlya vrachey [Veloergometry. A practical guide for doctors]. Saint-Petersburg, RF: 2007. 138 p.
- Fitz Gerald JM, Poureslami I. The need for humanomics in the era of genomics and the challenge of chronic disease management. Chest. 2014;146:10-2.
- Zhang H, Gustafsson M, Nestor C. Targeted omics and systems medicine: personalizing care. Lancet Respir Med. 2014;2(10):785-7.
- Ismoilov KI, Saburova AM, Sharipova MM. Antioksidantnaya zashchita i osobennosty perekisnogo okisleniya lipidov pri bronkhial’noy astme u detey [Antioxidant defense and peculiarities of lipid peroxidation in children with bronchial asthma]. Vestnik Avitsenny [Avicenna Bulletin]. 2017;19(1):73-7. Available from: http://dx.doi.org/10.25005/2074-0581-2018-19-1-73-77.
Authors' information:
Ismoilov Komildzhon Isroilovich,
Doctor of Medical Sciences, Full Professor, Head of the Department of Pediatric Diseases № 2, Avicenna Tajik State Medical University
Sharipova Mavluda Mirzomuddinovna,
Postgraduate Student of the Department of Pediatric Diseases № 2, Avicenna Tajik State Medical University
Conflicts of interest: No conflict
Address for correspondence:
Sharipova Mavluda Mirzomuddinovna
Postgraduate Student of the Department of Pediatric Diseases № 2, Avicenna Tajik State Medical University
734003, Republic of Tajikistan, Dushanbe, Rudaki Ave., 139
Tel.: +992 (881) 880809
E-mail: mavluda.sharipova.1988@mail.ru
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