Pharmacology

doi: 10.25005/2074-0581-2018-20-4-421-426
MOLECULAR APPROACH TO DETERMINE THE HOT AND COLD TEMPERAMENTS IN PLANTS ACCORDING AVICENNA CONCEPTS, THE ROLE OF MAGNESIUM

M. Sharofova1,2, I. Aldybiat3, Sh. Sagdieva1, N. Burkhonova1, Yu. Nuraliev2,4, F. Rahimi1, M. Mirshahi1,3

1Research Center for Innovative Technologies, Academy of Sciences of the Republic of Tajikistan, Dushanbe, Republic of Tajikistan
2Institute of Avicenna’s Medicine and Pharmacology, Dushanbe, Republic of Tajikistan
3University of Sorbonne Paris Cité-Paris 7, Lariboisière Hospital, INSERM U965, 75010 Paris, France
4Central Scientific-Research Laboratory, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan

Objective: The molecular approach of millenary notion about hot and cold temperaments (mizaj) in plants according to Avicenna concepts is not investigated. The aim of this study is to analyze the correlation between mizaj property of plants from the Tajikistan area and their amount/quality of metal.

Methods: We analyzed the presence of several metals that implicated in body’s homeostasis integrity, such as sodium, potassium, calcium, and magnesium, in several edible plants (n=23) from different regions in Tajikistan. Samples (n=43) of plant’s parts including seeds, flower, leaf, stem and root were analyzed for their elements’ composition using Energy Dispersive X-Ray Analysis (EDX) which incorporates Scanning Electron Microscopy (SEM).

Results: We didn’t find any correlation between the area of the collected samples and the amount of metal absorbance by the plants. The metals distributions of plant’s parts varied from one to the other. In this study, we found strict correlation between the amount of magnesium and the temperament properties of the plants reported by Avicenna. The magnesium was detected in high amount in Achillea millefolium L., Rosa canina L., Coriandrum sativum L., Foeniculum vulgare Mill. and Nigella sativa L.

Conclusions: The presence of high concentration of magnesium in the edible plants can be considered as a metal contribution (factor) in hot mizaj property and may lead to energy regeneration and wellbeing after consumption.

Keywords: Metal, hot and cold nature, plants, Avicenna, magnesium, Tajikistan.

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Authors informations:

Sharofova Mizhgona, Candidate of Medical Sciences, Head of the Laboratory of Biotechnology, Research Center for Innovative Technologies, Academy of Sciences of the Republic of Tajikistan; Director of the Institute of Avicenna’s Medicine and Pharmacology

Aldybiat Iman, PhD, Post Doctorant in University of Sorbonne Paris Cité-Paris 7, Lariboisière Hospital

Sagdieva Shoista, Candidate of Medical Sciences, Senior Researcher of the Laboratory of Biological Sciences, Research Center for Innovative Technologies, Academy of Sciences of the Republic of Tajikistan

Burkhonova Nigora, Junior Researcher of the Laboratory of Biotechnology, Research Center for Innovative Technologies, Academy of Sciences of the Republic of Tajikistan

Nuraliev Yusuf, Doctor of Medical Sciences, Honorary Professor of the Central Scientific-Research Laboratory, Avicenna Tajik State Medical University; Co- Director of the Institute of Avicenna’s Medicine and Pharmacology

Rahimi Farhod, Doctor of Physical and Mathematical Sciences, Professor, Academician and President of the Academy of Sciences of the Republic of Tajikistan

Mirshahi Massoud, Professor, MD, PhD, University of Sorbonne Paris Cité- Paris 7, Lariboisière Hospital, Member of the Academy of Sciences of the Republic of Tajikistan

Address for correspondence:

Massoud Mirshahi MD, PhD
Université de Sorbonne Paris Cité UMR Paris 7, INSERM U965 Carcinose, Angiogenèse et Recherche Translationnelle L’Hôpital Lariboisière 41 Bd de la Chapelle

75010, Paris, France

Tel.: 00 33 1 53216775

Fax: 00 33 1 53216739

E-mail: massoud.mirshahi@inserm.fr

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