Public Health and Preventive Medicine
doi: 10.25005/2074-0581-2020-22-1-74-81
CONTENT-ANALYSIS OF THE PHARMACEUTICAL MARKET OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS IN GROUPS OF ACETIC ACID DERIVATIVES IN THE KYRGYZ REPUBLIC

D.U. Ermekova1, I.Z. Ismailov2

1Institute of Chemistry and Phytotechnology of the National Academy of Sciences of the Kyrgyz Republic, Bishkek, Kyrgyz Republic
2Department of Basic and Clinical Pharmacology, I.K. Akhunbaev Kyrgyz State Medical Academy, Bishkek, Kyrgyz Republic

Objective: To segment the pharmaceutical market of non-steroidal anti-inflammatory drugs (NSAIDs) of the derivatives groups of acetic acid in the Kyrgyz Republic.

Methods: The database of the State Registry of Medicines registered and approved for Medical use in Kyrgyzstan, the Department of Drugs Security and Medical Engineering of the Ministry of Health of the Kyrgyz Republic is used for analysis.

Results: Analysis showed that the leaders of the pharmaceutical market in Kyrgyzstan the number of registered medicines (M) under the trade names are Medical Drugs (MD) with international generic name: diclofenac, ketorolac, indomethacin. It has been established that there are 99 trade names of NSAIDs of the groups of acetic acid derivatives in the Kyrgyz pharmaceutical market. The largest part of the range consists of diclofenac (M01AB05), represented by 62 trade names MD (62.6%), and ketorolac (M01AB15), represented by 20 trade names MD (20.2%). In the pharmaceutical market of Kyrgyzstan are NSAIDs from the groups of acetic acid derivatives from 15 countries, of which 21.1% of MDs are produced by neighboring countries, and 73.3% – in far countries. Conducted studies have revealed that the structure of the range of NSAIDs groups of acetic acid derivatives is dominated by soft medicinal forms, which making up 37.4%. A comparative analysis of the composition of MD by the number of active substances revealed that 92.9% of NSAIDs of the groups of acetic acid derivatives are monodrugs. Based on the analysis of the price segmentation of NSAIDs of the groups of acetic acid derivatives, most of the drugs are in the low-price segment.

Conclusion: A sufficient assortment saturation of the pharmaceutical market of Kyrgyzstan NSAIDs groups of acetic acid derivatives has been revealed. The pharmaceutical market of the Kyrgyz Republic is dominated by monocomponent NSAIDs in the form of soft medicinal forms produced in foreign countries. Only 7 MDs from this group are in the high-price range, making the remaining drugs financially available to consumers.

Keywords: NSAIDs, indomethacin, diclofenac, etodolac, ketorolac, aceclophenac.

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Authors' information:

Ermekova Dinara Urmatovna
Postgraduate Student, Institute of Chemistry and Phytotechnology of the National Academy of Sciences of the Kyrgyz Republic
ORCID ID: 0000-0002-6049-2380
E-mail: dinaermekova.de@mail.ru

Ismailov Isabek Zaylidinovich
Doctor of Pharmaceutical Sciences, Associate Professor, Department of Basic and Clinical Pharmacology, I.K. Akhunbaev Kyrgyz State Medical Academy
Researcher ID: B-7280-2017
SCOPUS: 57189622130
ORCID ID: 0000-0003-4980-8986
Author ID: 805452
SPIN: 7650-2129
E-mail: ism-isa@mail.ru

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:

Ismailov Isabek Zaylidinovich
Doctor of Pharmaceutical Sciences, Associate Professor, Department of Basic and Clinical Pharmacology, I.K. Akhunbaev Kyrgyz State Medical Academy

720020, Kyrgyz Republic, Bishkek, Akhunbaev Str., 92

Tel.: +996 (559) 639777

E-mail: ism-isa@mail.ru

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