CASE REPORT
Neurology
doi: 10.25005/2074-0581-2024-26-3-508-518
WERNICKE ENCEPHALOPATHY FOLLOWING BARIATRIC SURGERY: CASE REPORT

L.R. AKHMADEEVA1,2, O.V. GALIMOV3, D.E. BAYKOV4, Z.F. MAVLYANOVA5, O.A. KIM5, E.M. MAMYTOVA6

1Department of Neurology, Bashkir State Medical University, Ufa, Russian Federation
2Academy of Sciences of Bashkortostan Republic, Ufa, Russian Federation
3Department of Surgical Disorders and New Technologies, Bashkir State Medical University, Ufa, Russian Federation
4Department of General Surgery with Courses in Transplantology and Radiation Diagnostics, Bashkir State Medical University, Ufa, Russian Federation
5Department of Medical Rehabilitation, Sports Medicine and Traditional Medicine, Samarkand State Medical University, Samarkand, Republic of Uzbekistan
6Department of Neurology and Clinical Genetics named after A.M. Murzaliev, Kyrgyz State Medical Academy named after I.K. Akhunbaev, Bishkek, Republic of Kyrgyzstan

Objective: To review the signs and symptoms of Wernicke encephalopathy (WE) after bariatric surgery based on 2 case reports and a literature data analysis.

Methods: We present two case reports of WE. In these patients, thiamine deficiency developed due to bariatric gastric surgery, which was performed to treat class III obesity, formerly known as morbid obesity. The patients underwent comprehensive physical and neurological examinations; clinical, laboratory, and instrumental data were collected from medical records and analyzed. The researchers also performed a computerized search using the keywords "Wernicke encephalopathy after bariatric surgery" to find relevant publications in the PubMed/Medline, Scopus, and Web of Science databases.

Results: The presented acute neurological condition related to vitamin B1 deficiency in two patients after undergoing a weight loss surgery, specifically a mini-gastric bypass. The clinical picture in one patient was dominated by memory impairment, ataxic, and polyneuritic syndrome, while in the other, it was only polyneuritic syndrome.

Conclusion: The initial symptoms of WE are often overlooked, leading to the progression of the disease with the development of severe neurological deficits. To prevent the progression of encephalopathy, it is necessary to begin treatment with high doses of parenteral thiamine replacement therapy as early as possible.

Keywords: Obesity, bariatric surgery, Wernicke encephalopathy, thiamine, case report.

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References
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Authors' information:

Akhmadeeva Leyla Rinatovna,
Doctor of Medical Sciences, Professor of the Department of Neurology, Bashkir State Medical University; Professor of the Academy of Sciences of Bashkortostan Republic
Researcher ID: G-2624-2017
Scopus ID: 6505927195
ORCID ID: 0000-00002-1177-6424
SPIN: 1601-6079
Author ID: 96815
E-mail: Leila_ufa@mail.ru

Galimov Oleg Vladimirovich,
Doctor of Medical Sciences, Full Professor, Head of the Department of Surgical Diseases and New Technologies, Institute of Postgraduate Education, Bashkir State Medical University
Researcher ID: B-8212-2018
Scopus ID: 7003825111
ORCID ID: 0000-0003-4832-1682
SPIN: 8529-5508
Author ID: 128022
E-mail: galimovov@mail.ru

Baykov Denis Enverovich,
Professor of the Department of General Surgery with Courses in Transplantology and Radiation Diagnostics, Institute of Postgraduate Education, Bashkir State Medical University
ORCID ID: 0000-0002-3210-6593
E-mail: d-baikov@mail.ru

Mavlyanova Zilola Farkhadovna,
Doctor of Medical Sciences, Associate Professor, Head of the Department of Medical Rehabilitation, Sports Medicine and Traditional Medicine, Samarkand State Medical University
Scopus ID: 5722406396
ORCID ID: 0000-0001-7862-2625
E-mail: reab.sammi@mail.ru

Kim Olga Anatolievna,
Candidate of Medical Sciences, Assistant of the Department of Medical Rehabilitation, Sports Medicine and Traditional Medicine, Samarkand State Medical University
Scopus ID: 57220093236
ORCID: 0000-0003-1987-9505
E-mail: olanten@mail.ru

Mamytova Elmira Mitalipovna,
Doctor of Medical Sciences, Associate Professor, Head of the Department of Neurology and Clinical Genetics named after A.M. Murzaliev, Kyrgyz State Medical Academy named after I.K. Akhunbaev
Researcher ID: G-4653-2017
Scopus ID: 55622855400
ORCID ID: 0000-0002-4322-5555
SPIN: 4657-4393
Author ID: 842115
E-mail: elmiramamytova@yahoo.com

Information about support in the form of grants, equipment, medications

The work was carried out in accordance with the research plan of Bashkir State Medical University within the framework of the “Priority 2030” program. The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:

Mavlyanova Zilola Farkhadovna
Doctor of Medical Sciences, Associate Professor, Head of the Department of Medical Rehabilitation, Sports Medicine and Traditional Medicine, Samarkand State Medical University

140100, Republic of Uzbekistan, Samarkand, Amir Temur str., 18

Tel.: +998 (915) 229391

E-mail: reab.sammi@mail.ru


This work is licensed under a Creative Commons Attribution 4.0 International License.

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