Traumatology
doi: 10.25005/2074-0581-2019-21-2-274-278
EVALUATION OF THE EFFICIENCY OF ANTIRESORPTIVE THERAPY FOR OSTEOPOROSIS IN MULTIPAROUS WOMEN
Department of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Objective: To study the results of long continuous comprehensive treatment of osteoporosis in multiparous women on the background degenerative and dystrophic skeletal changes in the postmenopausal period.
Methods: A retrospective analysis of the results of treatment of 53 multiparous women on the background of degenerative and dystrophic skeletal changes in the postmenopausal period assessment in the dynamics of the level of Ca and Mg in serum, bone mineral density in the vertebral segment and proximal hip.
Results: It was found that after 3-6-18 months of treatment in 41 (77.4%) pain relief was observed, in 38 (71.1%) of serum calcium and magnesium increased in the case. X-ray showed marked increased clarity of the contours of the bones of the skeleton and an increase in bone mineral density (BMD) at the level of the vertebral segment by 7.4% (р<0.001) and in the proximal hip 3.6% (p<0.05).
Conclusion: The results of the study show that long continuous intake of antiresorptive drugs contributes to the activation of the process of bone remodeling, prevent further bone loss and achieve non-osteoporotic T-criterion values
Keywords: Osteoporosis, osteopenia, bone mineral density, postmenopausal period, calcium.
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Authors' information:
Mukhamedova Ilyura Galievna
, Assistant at the Department of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University
Razzokov Abduvali Abdukhamitovich
, Doctor of Medical Sciences, Full Professor, Head of the Department of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University
Ekhsonov Abdushokir Safarmatovich
, Applicant of the Department of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University
Conflicts of interest: No conflict
Address for correspondence:
Mukhamedova Ilyura Galievna
Assistant at the Department of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University
734003, Republic of Tajikistan, Dushanbe, Rudaki Ave., 139
Tel.: +992 (907) 807471
E-mail: muhamedova.iliura@yandex.ru
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- COMPARATIVE EVALUATION OF THE RESULTS OF TREATMENT OF UNSTABLE UNCOMPLICATED SPINAL FRACTURES
- PREVENTION OF POSTOPERATIVE COMPLICATIONS OF CALCANEUS FRACTURES
- AUTO-DYNAMIC INTRAMEDULLARY OSTEOSYNTHESIS FOR FEMUR FRACTURES AND CONSEQUENCES OF INJURIES
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- INVESTIGATION OF CALCIUM-PHOSPHORIC EXCHANGE IN WOMEN WITH THE MENOPAUSE STATE SUFFERING FROM OSTEOARTHROSIS AND CONCOMITANT OSTEOPENIC SYNDROME
- THE RESULTS OF TOTAL HIP JOINT ENDOPROSTHESIS FOR CONGENITAL HIP DISLOCATION
- COMPLICATIONS OF HIP JOINT ENDOPROSTHESIS
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