Traumatology

doi: 10.25005/2074-0581-2023-25-3-334-345
RISK FACTORS ASSOCIATED WITH IN-HOSPITAL MORTALITY AND PREDICTING OUTCOMES IN SEVERE ACUTE COMPOSITE TISSUE INJURIES

A.M. Naimov, A.A. Razzokov, F.M. Parpiev

Department of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan

Objective: To develop a reliable risk score prediction model to accurately predict the likelihood of lethal outcomes (LO) in severe acute composite tissue injuries (CTI) cases.

Methods: We conducted an analysis of data from 3,186 patients with CTIs who were aged between 18 and 74. Of these patients, 2,432 were men (76.3%), and 754 were women (23.7%). The age distribution of patients was as follows: 2290 (71.9%) were between 18-44 years old, 638 (20.0%) were between 45-59 years old, and 258 (8.1%) were between 60-74 years old. The patients with CTIs were split into two groups based on their diagnosis and treatment. The study group consisted of 1669 patients (52.4%) who received optimized approaches considering the likelihood of developing LO. The control group included 1517 patients (47.6%) diagnosed and treated using traditional methods. LO were noted in 514 (16.1%) cases. To determine the risk factors (RFs) associated with LO, we analyzed the distribution of frequency variables between lethal and non-lethal outcomes.

Results: The probability of developing LO in CTI was analyzed for statistical significance based on several RFs such as the patient's age, the presence of concomitant sub- and decompensated comorbid diseases, type and location of injury, severity of injuries, patient's state, and clinical forms of fat embolism syndrome (FES). Considering the identified RFs, a highly effective risk assessment scoring model for predicting the likelihood of developing LO in acute CTIs has been developed. Implementing optimized approaches and predicting the probability of developing LO significantly reduced fatality rates compared to traditional methods of diagnosis and treatment (13.5% and 18.5%, respectively, p<0.05).

Conclusion: Based on the testing results of the proposed scale with the significant decrease in LO observed in the study group, we highly recommend implementing these approaches in clinical practice.

Keywords: Composite injury, hospital mortality, optimized approach for diagnosis and treatment of composite trauma, scale for predicting lethal outcomes in concomitant injury.

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Authors' information:


Naimov Abdukarim Mamadrakhimovich,
Candidate of Medical Sciences, Assistant of the Department of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University
Researcher ID: HRB-5983-2023
ORCID ID: 0000-0001-7515-1696
E-mail: naimov.abdukarim@bk.ru

Razzokov Abduvali Abdukhamitovich,
Doctor of Medical Sciences, Full Professor, Professor of the Department of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University
Researcher ID: G-2628-2019
ORCID ID: 0000-0001-6429-1116
SPIN: 1768-1891
Author ID: 418277
E-mail: rfiruz@mail.ru

Parpiev Farkhad Merganboevich,
Assistant of the Department of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University
Researcher ID: HOH-8565-2023
ORCID ID: 0000-0001-9808-4078
SPIN: 5077-7839
E-mail: farhatparpiev1988@mail.ru

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:


Naimov Abdukarim Mamadrakhimovich
Candidate of Medical Sciences, Assistant of the Department of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University

734003, Republic of Tajikistan, Dushanbe, Rudaki Ave., 139

Tel.: +992 (918) 888822

E-mail: naimov.abdukarim@bk.ru

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