REVIEW ARTICLE
Pediatrics
doi: 10.25005/2074-0581-2025-27-3-712-722
DEVELOPMENT OF APPROACHES TO TREATMENT OF CHILDREN WITH RARE AUTOIMMUNE DISEASES: A PHILOSOPHICAL PERSPECTIVE REVIEW

A.YU. KUGUSHEV1,2, A.B. LOPATIN3,4, S. DAGHER3

1Department of Maxillofacial Surgery and Surgical Dentistry, Pirogov Russian National Research Medical University, Moscow, Russian Federation
2Department of Maxillofacial Surgery, Russian Childrens’ Clinical Hospital, Moscow, Russian Federation
3Dmitry Rogachev National Medical Research Center of Pediatric Hematology and Immunology, Moscow, Russian Federation
4Department of Oral and Maxillofacial Surgery, Peoples' Friendship University of Russia named after Patrice Lumumba, Moscow, Russian Federation

Due to the lack of comprehensive clinical studies, many rare diseases in children remain poorly understood and pose a serious threat to the lives of young patients who suffer from them. For years, philosophers and psychologists have sought ways to alleviate the psychological impact of these illnesses on children. This active search has led to the development of various philosophical approaches that offer solutions to the challenges faced by these children and their families.

It is widely recognized that immune disorders play a significant role in the disease spectrum, and ongoing research aims to enhance the understanding of these conditions. Among the autoimmune diseases that commonly affect children, primary chronic osteomyelitis stands out as a disease of unknown origin. Many countries worldwide are actively engaged in collective initiatives to create national strategies focused on providing medical care to children facing challenges due to rare diseases.

For this literature review, several resources were utilized, including PubMed, Scopus, Web of Science, eLibrary, and Cyberleninka, covering the past decade. The following keywords were used in the search: philosophy, rare diseases, history of immune diseases, children, medical care, and primary chronic osteomyelitis. The search yielded thousands of articles and e-books containing these keywords, from which articles published in peer-reviewed and reputable journals were selected. Sources that were not fully accessible were excluded, either because they were published in closed journals or because only a small portion of the book was available online.

Keywords: Primary chronic osteomyelitis, rare diseases, autoimmune diseases, medical care for children.

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Authors' information:

Kugushev Aleksandr Yurievich,
Doctor of Medical Sciences, Lecturer at the Department of Maxillofacial Surgery and Surgical Dentistry, Pirogov Russian National Research Medical University; Maxillofacial Surgeon at the Department of Oral and Maxillofacial Surgery, Russian Children's Clinical Hospital
ORCID ID: 0000-0002-6881-7709
E-mail: drkuguzhev@gmail.com

Lopatin Andrey Vyacheslavovich,
Doctor of Medical Sciences, Full Professor, Maxillofacial Surgeon at Dmitry Rogachev National Medical Research Center of Pediatric Hematology and Immunology; Lecturer at the Department of Oral and Maxillofacial Surgery, Peoples' Friendship University of Russia named after Patrice Lumumba
ORCID ID: 0000-0003-0043-9059
E-mail: and-lopatin@yandex.ru

Dagher Suzan,
Postgraduate Student, Department of Oral and Maxillofacial Surgery, Peoples' Friendship University of Russia named after Patrice Lumumba
ORCID ID: 0009-0004-1950-4011
E-mail: suzandager@yandex.com

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:

Dagher Suzan
Postgraduate Student, Department of Oral and Maxillofacial Surgery, Peoples' Friendship University of Russia named after Patrice Lumumba

117198, Russian Federation, Moscow, Miklukho-Maklaya str., 10

Tel.: +7 (991) 6114298

E-mail: suzandager@yandex.com


This work is licensed under a Creative Commons Attribution 4.0 International License.

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