Pediatrics
doi: 10.25005/2074-0581-2025-27-3-776-789
MICROVASCULAR BED CHARACTERISTICS IN A CHILD WITH SEVERE UNCONTROLLED BRONCHIAL ASTHMA: A CASE REPORT AND LITERATURE REVIEW

A.E. KHURGAEVA1, T.A. GUTYRCHIK1, SH.A. GITINOV1,2, A.B. MALAKHOV1,3,4, O.YU. BRUNOVA1, P.V. BEREZHANSKIY1,2,4

1Morozov Children's Clinical Hospital, Moscow, Russian Federation
2People’s Friendship University of Russia named after Patrice Lumumba, Moscow, Russian Federation
3Research Clinical Institute of Childhood, Moscow Region, Russian Federation
4I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation

As per available data, pediatric bronchial asthma (BA) is classified into four categories: atopic/allergic (80.2%), unspecified (17.4%), mixed (2.1%), and non-allergic/non-atopic BA (0.3%). The burden of BA is considered a significant public health concern due to its high disability rate, which leads to areduced quality of life and considerable economic losses for society. Therefore, timely diagnosis and treatment of pediatric BA are key public health priorities. In the era of evidence-based medicine, employing new diagnostic methods and identifying markers for disease development and prognosis are essential. One method used in diagnosing allergic diseases is nailfold capillaroscopy, which serves as a valuable additional criterion. This article presents a case of severe BA in a 12-year-old child. Due to poor compliance with treatment and the onset of status asthmaticus, nailfold capillaroscopy was performed in the intensive care unit to examine microcirculatory and hemodynamic changes associated with severe atopic BA. A comprehensive diagnostic approach and appropriate treatment led to significant improvement in the patient's condition.

Keywords: Bronchial asthma, phenotypes, endotypes, severe bronchial asthma, nailfold capillaroscopy, case report.

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Authors' information:

Khurgaeva Anastasia Eduardovna,
Pediatrician, Morozov Children's Clinical Hospital
ORCID ID: 0009-0009-0887-729X
SPIN: 2309-9893
E-mail: ipadmedic@mail.ru

Gutyrchik Tatyana Aleksandrovna,
Pediatrician, Morozov Children's Clinical Hospital
ORCID ID: 0000-0002-8421-1694
SPIN: 9592-5776
E-mail: tanya_2904@list.ru

Gitinov Shamil Abdulvakhidovich,
Pediatrician, Morozov Children's Clinical Hospital; Assistant of the Department of Pediatrics, Medical Institute, People’s Friendship University of Russia named after Patrice Lumumba
ORCID ID: 0000-0001-6232-544Х
SPIN: 7062-6008
E-mail: dr.gitinov@mail.ru

Malakhov Aleksandr Borisovich,
Doctor of Medical Sciences, Professor of the Department of Children's Diseases, I.M. Sechenov First Moscow State Medical University; Head of the Pediatrics Department, Research Clinical Institute of Childhood; Pulmonologist, Morozov Children's Clinical Hospital
ORCID ID: 0000-0002-2686-8284
SPIN: 1749-0503
E-mail: alexis4591m@mail.ru

Brunova Olga Yurievna,
Head of the Department of Resuscitation and Intensive Care, Morozov Children's Clinical Hospital.
ORCID ID: 000-003-2158-6672
E-mail: BrunovaOY@zdrav.mos.ru

Berezhanskiy Pavel Vyacheslavovich,
Doctor of Medical Sciences, Assistant of the Department of Children's Diseases, I.M. Sechenov First Moscow State Medical University; Pulmonologist, Morozov Children's Clinical Hospital; Assistant of the Department of Clinical Immunology, Allergology and Adaptology, People’s Friendship University of Russia named after Patrice Lumumba
ORCID ID: 0000-0001-5235-5303
SPIN: 1480-9900
E-mail: p.berezhanskiy@mail.ru

Information about support in the form of grants, equipment, medications

The authors did not receive financial support from manufacturers of medicines and medical equipment

Conflicts of interest: No conflict

Address for correspondence:

Khurgaeva Anastasia Eduardovna
Pediatrician, Morozov Children's Clinical Hospital

119049, Russian Federation, Moscow, 4th Dobryninsky lane, 1/7

Tel.: +7 (937) 3947777

E-mail: ipadmedic@mail.ru


This work is licensed under a Creative Commons Attribution 4.0 International License.

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