Summary

doi: 10.25005/2074-0581-2009-11-3-91-96
CLINIC MORPHOLOGICAL CHARACTERISTICS OF OBTAINED IMMUNE-DEFICIT SYNDROME UNDER CHRONIC DRUG ADDICTION AND CHRONIC ALCOHOL INTOXICATION

Yu.I. Pigolkin, A.B. Gasanov, R.A. Tursunov, Z.K. Hushkadamov

For studying purposes of clinic morphological peculiarities of IDS under chronic drug addiction (CDA) and chronic alcohol intoxication (CAI) results of 335 autopsies were observed, pathomorphological alterations of immune organs and endocrine glands were analyzed. It was shown that IDS under CDA and CAI is taking its stage course through stages of compensation and decompensation. The compensation is because the activity of humoral immunity; stage-duration and compensation-degree connect from type, dose and the time of toxicity, indnvidual genetic and age peculiarities. Small once doses of narcotics may influence transitor-stimulation of immune system. Severity of injury of endocrine system connects from duration and severity of CAI. Features of CDA and CAI have likeness and some special pecualirities.

Keywords: drug addiction, chronic alcohol intoxication, immune system, endocrine glands, immunedeficiency syndrome.

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