Summary

doi: 10.25005/2074-0581-2010-12-3-85-89
The possibility of basic parameters of blood kinin system correction in patients with myocardial infarction complicated by cardiogenic shock

N.Kh. Olimov, Kh.R. Vokhidov, E.Ch. Yuldoshev

Among 80 patients with myocardial infarction (MI) complicated by cardiogenic shock a blood kallikrein-kinin system (KKS) parameters have been estimated. It was determined that KKS activity increased threefold in these patients. Contrical has been administrated on the background of antishock therapy for the purpose of activity dropping as the main inhibitor of KKS. It was detected that KKS activity was depressed and clinical condition of patients in the main group was improved after contrical therapy. It was observed improvement on ECG, intracardiac haemodynamics indices were made better according to echocardiogram and lethality from cardiogenic shock is reduced.

Keywords: myocardial infarction, cardiogenic shock, kallikrein-kinin blood system.

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