Role of immunotherapy in complex treatment of iron deficiency anemia in children

K.I. Ismailov, N.N. Khojaeva

Chair of Children’s Diseases № 2 Avicenna TSMU

In order to evaluate the effectiveness of immunotherapy in the treatment of iron deficiency anemia (IDA) were analyzed findings of 40 patients with anemia of moderate and severe degree, 18 of them (45%) boys and 22 (55%) – the girls. The control group consisted of 20 healthy children.

Revealed that children with moderate and severe IDA is observed decrease of cellular (CD4 20,1±1,84; 15,7±0,28; CD8 14,3±0,35; 10,6±1,33) and humoral (CD20 13,1±0,71; 9,8±1,33) immunity, which has a direct correlation to the severity of the pathological process. Thus the frequency of intercurrent diseases increases in direct proportion to the severity of anemia.

The complex antianaemia and immunotherapy was conducted, which has led to improving of cellular and humoral immunity. This has resulted in a marked decrease (2-fold) of intercurrent disease in this group of patients. This was a proof of therapy effectiveness.

Keywords: iron deficiency anemia, intercurrent diseases, immunity, immunotherapy.

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