Antibiotic prophylaxis of postoperative wound infectious-inflammatory complications in abdominal surgery

Sh.K. Nazarov, H.N. Alimov

Chair of Surgical Diseases №1 Avicenna TSMU

The experience of carrying antibiotic prophylaxis of postoperative wound infectious and inflammatory complications in surgery of the abdominal cavity in 154 patients with various surgical abdominal pathologyare presented in the article.

Before surgery to patients of the main group (n=79), given the nature of the disease and the amount of the forthcoming operation, administered the broad-spectrum antibiotics, particularly drug «Belasef» (ceftriaxone) 1 g i / m; to patients of the control group (n=75) – after surgery.

In both groups, including gram-positive microflora often sown Gram-positive rods, and staphylococci. The main representatives of gram-negative microflora were E.coli (17,9%), Citrobacter spp. (15,3%) and Acinetobacter spp. (3,4%).

Upon completion of operations, the study group showed only a slight increase in microbial contamination of the skin, only in polluted type of operation (3,5x102 microbial cells per 1 sm2 ). In the control group of microbial contamination of the skin at the end of operations, content increased to 3,7x102 , when dirty – to 4,4xsm2  microbial cells per 1sm2 . When a dirty type of operations only in 12 (15,1%) patients of the main group and 14 (18,6%) – the control group was isolated S.epidermidis, and the remaining patients sown negative microflora (E.coli, Enterobacter spp., Proteus spp., P.aeruginosa and other Gram-negative non-fermentative bacteria).

Keywords: antibiotic, infectious-inflammatory complications, surgery of the abdominal cavity.

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