State of platelet hemostasis in children of the first year of life in bacterial pneumonia

K.I. Ismoilov, S.T. Davlatov, M.A. Ismoilova

Chair of Children Diseases №2 Avicenna TSMU

This article presents the results of a study platelet hemostasis in 71 newborns and infants with bacterial pneumonia.

Children depending on the severity of pneumonic process were divided into two groups. The first group consisted of 38 children with severe, the second – 33 patients with very severe pneumonia.

During platelet hemostasis investigations in patients of the first group was found aapparent (3,9±0,07 min; p<0,05), and the children of the second group - a significant (6,3±0,009 min; p<0,001) elongation of bleeding time by Duke. The degree of endothelial «pinch» samples and retraction of blood clot formation in patients of the first group was more likely to moderate (1,35±0,01 degree; 44,4±3,81%, respectively), whereas in patients of the second group – a significant (2,15±0,003 v; 36,7±4,15%). The total number of peripheral blood platelets in majority of the first group patients had a moderately reduced and ranged from 80 to 160х109/l, whereas in second group of patients it was significantly reduced (94,4х109/l). Thus, in patients with a severe form of pneumonia observed moderate, and in patients with very severe course of pneumonic process – severely impaired platelet hemostasis.

Keywords: bacterial pneumonia, hemostasis.

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