Dysbacteriosis in chronic duodenal obstruction syndrome

P. Vahobzoda, A. Dustov, S.M. Asimova, V.Sh. Sharipov

State Institution «Institute of Gastroenterology» AMS Ministry of Health and Social Protection of the Republic of Tajikistan

The article presents the results of a comprehensive examination and treatment of 80 patients with chronic duodenal obstruction (CDO). The average age of patients was 43,1±3,6 years. Given the important role of intestine biocenosis in CDO, a study of intestinal dysbiosis severity in all patients was conducted.

The severity of dysbiosis has a direct relationship to the compensation stage of CDO that found during study. Patients with CDO dysbacteriosis in compensation stage I-III degree occurred in 58,4%, whereas in decompensated stage this index was equal to 93,8%. With the reduction of indicators of normal intestinal flora observed high titers of conditionally pathogenic flora, reaching from 1×107 to 1×109 zooid.

Evaluation of the sensitivity of colon enterobacteria to antimicrobial medications revealed a high sensitivity to Tetracycline in patients with CDO, which was 83,3% for patients in compensation stage and 87,5% – in decompensation one, sensitivity to Furazolidone – 87,5% and 81,2%, respectively.

Keywords: chronic duodenal obstruction, dysbacteriosis, intestinal microflora, bifidoflora and lactoflora.

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